Browsing by Subject "cell motility"
Now showing items 1-9 of 9
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(2007-04-11)Department: Cell and Developmental BiologyThe work contained in this document describes the generation of new immunoreagents for Bves study, and our identification of a Bves-interacting protein. After generating new monoclonal antibodies to the Bves protein, I ...
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(2006-12-04)Department: Biomedical EngineeringCorneal wound healing is a complex, and highly coordinated process of cell-cell signaling, cell spreading, migration, proliferation, and cell-extracellular matrix interaction. The main limitation in natural wound healing ...
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(2010-08-02)Department: Cell and Developmental BiologyThis project provides a detailed characterization of the CLASP-dependent microtubule array at the Golgi in terms of function and regulation. First, I briefly outline the process of MT nucleation at the Golgi and highlight ...
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(2007-04-06)Department: Cancer BiologyIntegration of receptor tyrosine kinase, integrin, and cadherin activities is crucial for normal cell growth, motility and adhesion. Here, we describe novel roles for p120 catenin (p120) and p190RhoGAP that coordinate ...
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(2009-09-11)Department: Biological SciencesProstaglandin E2 (PGE2) influences many processes in vertebrates, including development, homeostasis, and disease through its GPCRs EP receptors 1-4. PGE2 regulates gastrulation movements during zebrafish embryogenesis, ...
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(2012-06-05)Department: Biomedical EngineeringCell motility plays an important role in development, wound healing and cancer progression. A fundamental unresolved challenge in the field is to obtain reliable measures of motility metrics from single cells and then ...
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(2018-04-12)Department: Cancer BiologyCell motility is a process tightly linked to tumor metastasis. The p21-activated kinases (PAKs) are modulators of cell motility commonly overexpressed and hyperactive in various malignancies. We investigated whether ...
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(2010-07-14)Department: Cell and Developmental BiologyFocal adhesions (FAs) are sites at the interface between the cell and the ECM, linking integrin receptors and the actin cytoskeleton. In addition to serving as a structural platform, these sites are also robust sites of ...
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(2010-02-16)Department: PharmacologyCell motility plays important roles in development, wound healing, and metastasis. Cells move either spontaneously, in a non-directed fashion, or in response to chemotactic signals, in a directed fashion. Even though they ...