Now showing items 1-7 of 7

    • Stauffer, Kim; 0000-0002-2605-9356 (2022-02-02)
      Department: Molecular Pathology & Immunology
      Cancer resequencing studies have revealed epigenetic enzymes as common targets for recurrent mutations. The monomethyltransferase MLL3 is among the most recurrently mutated enzymes in ER+ breast cancer. The H3K4me1 marks ...
    • Pilewski, Kelsey Angelica; 0000-0003-0916-4098 (2022-03-27)
      Department: Molecular Pathology & Immunology
      Vaccines represent one of the most successful medical interventions in history, and their efficacy is dependent on the induction of a robust and long-lasting immune response, classically through the elicitation of neutralizing ...
    • Madden, Matthew Zachary; 0000-0003-4062-4427 (2022-05-11)
      Department: Molecular Pathology & Immunology
      Metabolism determines cell function and fate across tissues and disease states. Proliferative cells upregulate anabolic metabolism to support cell growth, division, and other activities. Glucose and glutamine are critical ...
    • Klopfenstein, Nathan; 0000-0001-5220-4345 (2021-09-16)
      Department: Molecular Pathology & Immunology
      Methicillin-resistant Staphylococcus aureus (MRSA) is a major cause of skin and soft tissue infections in health care settings and those with diabetes worldwide. There is an unmet clinical need to develop new immunotherapeutic ...
    • Hadadianpour, Azadeh; 0000-0001-5581-7112 (2022-03-02)
      Department: Molecular Pathology & Immunology
      One-third of all humans, more than 1.5 billion people living in developing countries, are suffering from helminth infection. A vigorous type 2 immune response, characterized by highly elevated levels of IgE, is the hallmark ...
    • Kramer, Kevin John; 0000-0001-8451-9018 (2021-09-08)
      Department: Molecular Pathology & Immunology
      The COVID-19 pandemic, caused by the novel coronavirus SARS-CoV-2, has resulted in the illness and death of millions of people worldwide. Although medical countermeasures including monoclonal antibody cocktails and vaccines ...
    • McNew, Kelsey; 0000-0001-8399-831X (2022-03-02)
      Department: Molecular Pathology & Immunology
      Type 1 Diabetes (T1D) is an autoimmune disease characterized by destruction of the pancreatic beta cells by autoreactive lymphocytes. While autoreactive CD8+ T cells, CD4+ T cells, and B cells collaborate to destroy beta ...