Unfortunately, the current re-excision rates for breast conserving surgeries due to positive margins average 20-40%. The high re-excision rates arise from difficulty in localizing tumor boundaries intraoperatively and lack ...

Assessment of the restoration of load-bearing function is the central goal in the study of fracture healing process. During the fracture healing, two critical aspects affect its analysis: (1) material properties of the ...

Living cells and tissues experience mechanical forces in their physiological environments that are known to affect many cellular processes. Also of importance are the mechanical properties of cells, as well as the microforces ...

The goal of this work is to develop and demonstrate a novel model of superparamagnetic iron oxide nanoparticle (SPION) magnetic properties based on physical first principles and experimental mathematical relationships. ...

A major challenge in endocrine surgery is the intraoperative identification of parathyroid during both thyroid and parathyroid surgery. Current localization techniques are mostly preoperative and are imprecise. Optical ...

We present a multi-dye ratiometric method for the correction of optical artifacts and unequal illumination encountered by researchers that utilize complex microfluidic systems. Using a novel chemotaxis system that provides ...

Point-of-care diagnostics suitable for the resource-limited environment should be low-cost and simple-to-use while maintaining a clinically meaningful performance capability. This thesis explores harnessing the hydrodynamics ...

The failure of synthetic vascular grafts due to de-endothelialization of the lumen as a result of exposure to fluid-induced shear stress prevents the widespread use of such grafts as small-diameter vessel replacements. ...

As chikungunya, dengue, and Zika virus infections all present similar symptoms, a multiplexed assay could provide enhanced diagnostic power to clinicians at the point-of-care in low-resource settings: a patient with these ...

TBD