Browsing by Author "R. Daniel Beauchamp"
Now showing items 1-5 of 5
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Johnson, Jeffery Chad (2007-08-14)Department: Cancer BiologyCyclooxygenase-2 (COX-2) has long been known to be a facilitator of colorectal neoplasia, specifically in the development and progression of adenomatous polyps to colorectal carcinoma. The purpose of the studies conducted ...
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Kanies, Cindy Lynn (2008-04-07)Department: Cancer BiologyColon cancer progression is frequently characterized by activating mutations in Ras and emergence of the tumor promoting effects of TGF-beta signaling. Ras-inducible rat intestinal epithelial cells (RIE:iRas) undergo a ...
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Al-Greene, Nicole Theresa (2013-10-09)Department: Cell and Developmental BiologyThe role of Four jointed box 1 (FJX1) in colorectal cancer (CRC) is presented in this dissertation. FJX1 was identified as a candidate gene for regulating tumor formation in CRC as it was inhibited in rectal cancers after ...
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Castellanos, Jason Alfred (2016-06-15)Department: Biomedical InformaticsColorectal Cancer (CRC) remains a leading cause of cancer-related mortality in the United States. A key therapeutic dilemma in the treatment of CRC is whether patients with stage II and stage III disease require adjuvant ...
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Pope, Jillian Lashea (2014-04-08)Department: Cancer BiologyPerturbation of physiological processes stimulate a cascade of events resulting in adverse pathogical conditions, the most predominant being cancer. Colorectal cancer (CRC) is the third most common cancer in the United ...