Browsing by Author "Christine Konradi"
Now showing items 1-11 of 11
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Coppola, Jennifer Judith (2019-07-16)Department: PsychologyAcetylcholine (ACh) is a ubiquitous and well-studied neurotransmitter, best characterized in the peripheral nervous system where it acts as the signaling molecule at the neuromuscular junction. Despite being among the first ...
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Moore-Lotridge, Stephanie Nicole (2018-11-20)Department: PharmacologyCalcium and phosphate are essential elements in many biological processes, such as basic cellular function and signaling, yet they also combined to make biological crystals, most notably hydroxyapatite found in bone. ...
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Schmidt, Martin Jefferson (2014-04-09)Department: NeuroscienceGABA-ergic disturbances are hallmark features of many brain disorders. Two transgenic mouse lines were generated to suppress GAD1 in non-overlapping cell types that express cholecystokinin (CCK) or neuropeptide Y (NPY). ...
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Sillivan, Stephanie Elizabeth (2011-12-04)Department: NeuroscienceEmbryonic dopamine (DA) receptor (DR) expression in the medial frontal cortex (mFC) coincides with the formation of neural circuits during the period of axon pathfinding but the signaling properties of DRs and their effect ...
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Gamble-George, Joyonna Carrie (2016-08-01)Department: NeuroscienceCannabinoid receptors have been examined as potential targets to alleviate the negative consequences of anxiety, trauma-related, and stress-related disorders. However, in preclinical animal studies, synthetic cannabinoids ...
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Mitchell, Amanda Christine (2011-12-09)Department: NeuroscienceMild, moderate, and vigorous physical activity are associated with decreased risks of Alzheimer’s disease, Parkinson’s disease, and a decreased infarct from stroke. Physical activity increases neurogenesis in the hippocampus ...
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Bender, Brian Joseph (2019-01-17)Department: PharmacologyG-protein coupled receptors (GPCRs) represent the largest family of membrane proteins and the most heavily targeted classes of proteins for therapeutic intervention. Relatively little is known about the structure of these ...
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Manz, Kevin Michael (2019-12-05)Department: NeuroscienceThe nucleus accumbens (NAc) is implicated in the pathogenesis of conditions characterized by maladaptive motivational states, including addiction and depression. Embedded within the mesolimbic network, the NAc coordinates ...
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Joffe, Max Emanuel (2016-04-26)Department: PharmacologyDysregulation of the mesolimbic dopamine (DA) system is a hallmark of the pathophysiology of drug addiction and many other prevalent diseases. The nucleus accumbens (NAc), a region essential for the incentive and hedonic ...
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Echevarria, Franklin Daniel (2017-05-30)Department: NeuroscienceNeuroinflammation is defined as inflammation that occurs in the central nervous system (CNS) and is characterized by cytokine release and glial reactivity. Previous efforts indicate that neuroinflammation is involved in ...
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DelBove, Claire Elise (2018-08-03)Department: PharmacologyAmyloid precursor protein (APP) is a type I transmembrane protein and has been studied extensively due to its relevance to Alzheimer’s disease. However, its subcellular distribution and the mechanisms that regulate its ...