With the rise of antibiotic resistance, there is a growing need for compounds capable of non-bactericidal mechanisms that do not exert evolutionary pressure on the bacterium, such as biofilm modulators. Human milk ...

As diabetes continues to affect millions of people within the United States, identification of novel factors that may enhance beta-cell proliferation and mass regeneration in vivo is critical. Our lab previously demonstrated ...

In visual science research, awake animals traditionally are required to perform simple fixation tasks. Fixation can indeed simplify the situation because the spatial relationship between the visual objects and the retina ...

The serotonin transporter (SERT) mediates clearance of the neuromodulator serotonin (5-HT) following its release. The clinical efficacy of antidepressant drugs that block SERT activity indicates that serotonin transporter ...

Modulation of neurotransmitter exocytosis by activated Gi/o coupled G-protein coupled receptors (GPCRs) is a universal regulatory mechanism used both to avoid overstimulation and to influence circuitry. One of the known ...

This thesis is aimed at developing a better understanding of the cortical influence on computational maps at subcortical levels by studying how cortex modulates the tuning properties of thalamic relay neurons using rat’s ...

The main argument of this dissertation is that physical culture served as a powerful means to build the nation by molding Brazilian bodies and played a key role across many decades in multiple nationalist discourses. By ...

This thesis is concerned with the study of olfactory systems in both larval and adult mosquitoes. In this dissertation I cloned the first odorant receptor from mosquito Culex quinquefasciatus and localized the receptor ...

Neurofibromatosis type 1 results from mutations in NF1, a gene that encodes Neurofibromin. This common genetic condition is associated with tibial pseudarthrosis (PA), whose etiology is unknown but thought to involve ...