Browsing by Title
Now showing items 6982-7001 of 17443
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(2018)Kathleen Wilson writes that the domestic elite of Georgian Britain sought a psychological "disavowal" of the West Indian planting class because elite flaws were reflected in the perceived degeneracy and excess of the ...
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(2007-07-24)Department: Biomedical InformaticsRecent advances in single nucleotide polymorphism (SNP) genotyping techniques, public databases, and genomic knowledge via the Human Genome Project and the Haplotype Mapping project (HapMap) allow for true genome-wide ...
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(2018-01-17)Department: ChemistryDetermination of a protein’s structural equilibrium constitution remains a challenge. Experimental techniques like X-ray crystallography or nuclear magnetic resonance spectroscopy either are only able to determine single ...
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(2023-01-25)Department: Mechanical EngineeringAssessing the quality of an engine lubricant through real-time sensing could pave the way for remote monitoring of engine health and the development of machine learning algorithms for engine health management. However, ...
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(2013-12-12)Department: Biomedical EngineeringGelatin is a hydrolyzed and denatured form of collagen, which comprises the majority of extracellular matrix. Despite its numerous advantages for tissue engineering, its use as a thermostable hydrogel has been achieved ...
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(2012-11-06)Department: Interdisciplinary Materials ScienceA bottom up approach to functionalizing high quality porous silicon optical structures with nucleic acid bioreceptors is presented in this dissertation. The solid-phase synthesis method using phosphoramidite protected ...
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(MBIO, 2019-05)Helicobacter pylori colonizes about half of humans worldwide, and its presence in the gastric mucosa is associated with an increased risk of gastric adenocarcinoma, gastric lymphoma, and peptic ulcer disease. H. pylori ...
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(2013-12-18)Department: Earth and Environmental SciencesThe future of deltas worldwide will be determined by a balance of sedimentation, subsidence and sea-level rise, in addition to human-caused perturbations. The Ganges-Brahmaputra delta is perceived to be at great risk to ...
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(2020-07-24)Department: Environmental EngineeringFood, Energy, and Water (FEW) security is essential for human beings to live in modern societies. Challenges such as climate change and population growth made it much more difficult to achieve FEW security. This dissertation ...
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(2023-07-20)Department: Creative WritingA collection of poems exploring the coexistence of tenderness and violence within a framework of masculinity. Through narrative and lyric modes, the poems interrogate complex questions of beauty and sublimity as they ...
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(Vanderbilt University. Dept. of History, 2003-04-11)
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(2016-07-26)Department: AnthropologyThis dissertation provides a historical and anthropological analysis of sanctuary-city policy formation, power, and governance in San Francisco, California. This dissertation focuses on the discourses, practices, tactics, ...
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(Vanderbilt University. Dept. of History, 2010-04-30)
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(2008-12-15)Department: ChemistryExposure to endogenous and exogenous chemicals can lead to modification of DNA and potentially lead to cancer. Frameshift mutations may be a consequence of these modifications to DNA. Oligonucleotides were synthesized ...
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(2008-05-30)Department: BiochemistryHistone deacetylase 3 (HDAC3) is the enzymatic component of transcriptional repression complexes recruited by the nuclear hormone receptors. Inactivation of HDAC3 in cancer cell lines triggered apoptosis, and removal of ...
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(2009-04-20)Department: Biomedical EngineeringMRI provides an excellent way of visualizing muscle inflammation; however, there are few techniques that serve to quantitatively assess edematous muscle. In this thesis, integrated relaxation measurements were made in vivo ...
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(2010-02-09)Department: NeuroscienceTranscripts encoding 5HT2C receptors are modified posttranscriptionally by RNA editing, generating up to 24 protein isoforms. In recombinant cells, the fully edited isoform, 5HT2C-VGV, exhibits blunted G-protein coupling ...
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(2014-07-01)Department: Biomedical EngineeringHER2-amplified (HER2+) breast cancers are treated with the anti-HER2 monoclonal antibody trastuzumab. Although trastuzumab reduces production of the angiogenic factor VEGF in HER2+ tumors, the acute and sustained effects ...
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(2006-12-01)Department: Biomedical EngineeringThe islets of Langerhans play a central role in maintenance of glucose homeostasis. Apoptosis of the insulin-producing beta cells of the islet leads to diabetes mellitus. The ability to non-invasively image or assess the ...
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(SCIENTIFIC REPORTS, 2019-07-02)Imaging apoptosis could provide an early and specific means to monitor tumor responses to treatment. To date, despite numerous attempts to develop molecular imaging approaches, there is still no widely-accepted and reliable ...