Vanderbilt University Institutional Repository: Recent submissions
Now showing items 381-400 of 17735
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(2023-11-09)Department: Molecular Physiology & BiophysicsAntisense long non-coding RNAs (antisense lncRNAs) are ubiquitous in the human genome and important for many diseases and biological functions. Despite their importance, the mechanisms by which they exert their function ...
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(2023-11-16)Department: Leadership & Policy StudiesStudent-based budgeting (SBB), which combines weighted-student funding with site-based budgeting, has been adopted in several urban districts across the United States to help increase equity between and within schools as ...
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(2023-11-15)Department: Microbe-Host InteractionsHelicobacter pylori strains containing the cag pathogenicity island (PAI) are associated with the development of gastric adenocarcinoma and peptic ulcer disease. The cag PAI encodes a secreted effector protein (CagA) and ...
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(2023-11-15)Department: Chemical EngineeringTheoretical understanding of electrodiffusiophoresis (EDP) has advanced significantly in the last few decades. However, available studies lack direct experimental observations of EDP. In this dissertation, we provide direct ...
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(2023-11-13)Department: ReligionThe thesis of this dissertation is that Christian theology is captured in the metaphysical models of its time, which establish for theology what counts as reasonable and plausible. This thesis is explored in light of the ...
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(2023-11-17)Department: Biomedical EngineeringThe risk and burden of treating skin and soft tissue infections using antibiotic therapies is increasing due to the rising incidence of methicillin-resistant Staphylococcus aureus and other Gram-positive, multidrug-resistant ...
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(2023-11-15)Department: Cell & Developmental BiologyTransporting epithelia of the kidney and small intestine utilize actin-supported cell surface protrusions, known as microvilli, to expand surface area available for solute transport. Microvilli found on the surface of these ...
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(2023-11-16)Department: Civil EngineeringThis dissertation investigates the uncertainty quantification of prediction in high-dimensional problems. A systematic approach including adaptive surrogate modeling, discrepancy modeling and uncertainty propagation for ...
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(2023-11-21)Department: Cell & Developmental BiologyThe retinal pigment epithelium (RPE) is a monolayer of pigmented cuboidal cells that separates the retina from the choroid and is crucial for vision. Defective RPE function and RPE atrophy can often cause age-related macular ...
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(2023-11-16)Department: ChemistryThe cancer treatment regimen known as AC chemotherapy is one of the oldest and most commonly used regimens. Consisting of a combination of Adriamycin (Doxorubicin) and Cyclophosphamide, it has long been understood that the ...
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(2023-11-21)Department: Molecular Physiology & BiophysicsPancreatic islet insulin secretion is impaired during diabetes pathogenesis, due in part to disruption of β-cell Ca2+ handling. TALK-1 K+ channels are key regulators of ꞵ-cell electrical excitability, Ca2+ entry, and ...
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(2023-11-24)Department: GermanMy dissertation is a cross-disciplinary study of the Lustmord discourse from the late 19th century to the present that addresses questions of sexual violence, gender, and subjectivity through the framework of abject hegemony ...
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(2023-11-17)Department: Human GeneticsUterine fibroids (UF) are common benign tumors of the uterus affecting majority of females over their lifetime and are the number one cause of hysterectomies in the United States. Genetics are known to influence UF risk ...
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(2023-11-17)Department: HistoryThis dissertation project centers on the overlooked work of activists whose organizing efforts during the Black Power era converged with their subsequent initiation into African diasporic religions like Haitian Vodou or ...
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(2024)Alzheimer’s Disease (AD) is a disease with major symptoms including difficulties with memory, language, problem-solving, and other thinking skills. Given the current efforts in advocacy, policy, diagnosis, treatments, and ...
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(2023-11-17)Department: Human GeneticsDNA methylation is an epigenetic modification that is essential for proper multi-lineage cellular differentiation, though the connection between patterned regions of hypomethylation and phenotype is poorly understood. Over ...
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(2023-08-15)Department: NeuroscienceThe insular cortex (IC) integrates sensory and interoceptive cues to inform downstream circuitry executing adaptive behavioral responses. The IC communicates with areas involved canonically in stress and motivation. IC ...
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(2023-11-17)Department: Earth & Environmental SciencesThe Ora Ignimbrite (~275 Ma) is a crystal-rich (~40%), heterogeneous, supereruption-sized (~1,300 km3) rhyolite in northern Italy and the final eruptive product of the Athesian Volcanic Group (289 - 274 Ma), the largest ...
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(2023-11-17)Department: Earth & Environmental SciencesThe Ora Ignimbrite (~275 Ma) is a crystal-rich (~40%), heterogeneous, supereruption-sized (~1,300 km3) rhyolite in northern Italy and the final eruptive product of the Athesian Volcanic Group (289 - 274 Ma), the largest ...
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(2023-11-17)Department: Earth & Environmental SciencesThe Ora Ignimbrite (~275 Ma) is a crystal-rich (~40%), heterogeneous, supereruption-sized (~1,300 km3) rhyolite in northern Italy and the final eruptive product of the Athesian Volcanic Group (289 - 274 Ma), the largest ...