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The Role of the Prostaglandin E2 EP3 Receptor in Obesity, Insulin Resistance, and Glycemic Control
(2015-12-01)
Mice carrying a targeted disruption of the prostaglandin E2 E-prostanoid receptor 3 (EP3) gene, Ptger3, were fed a high-fat diet (HFD), or a micronutrient matched control diet, to investigate the effects of disrupted ...
Synaptotagmin IV and Myt factors promote β-cell functional maturation and maintenance
(2017-03-31)
Both type I and type II diabetes are related to β-cell defects in the pancreatic islet of Langerhans. Deriving β-cells from stem cells and other mature cell types provides an important cell source for transplantation-based ...
The Role of FoxM1 in Pancreatic Beta Cell Mass Regeneration and Expansion
(2008-09-29)
MOLECULAR PHYSIOLOGY AND BIOPHYSICS
THE ROLE OF FOXM1 IN PANCREATIC BETA CELL MASS
REGENERATION AND EXPANSION
AMANDA ACKERMANN MISFELDT
Dissertation under the direction of Maureen Gannon, Ph.D.
The size of an organism’s ...