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Variables that influence transcription factor-mediated acinar to beta cell reprogramming
(2017-02-24)
Reprogramming of pancreatic cells into new beta-like cells is a potential therapy for Type 1 diabetes. Pancreatic acinar cells are an appealing target for cellular reprogramming since they are abundant, derived from a ...
Examining the roles of MafB in the pancreatic islet
(2015-10-20)
Analysis of MafB-/- mice suggested that this transcription factor was essential to islet α- and β-cell formation during development, although the postnatal physiological impact could not be studied because these mutants ...