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Dopaminergic regulation of insulin secretion from the pancreatic islet
(2012-12-11)
Insulin secretion is the natural response to hyperglycemia, and it is crucial to maintain glucose homeostasis in healthy individuals. Impairment in this regulation eventually results in Type-2 diabetes. From the perspective ...
Structure-Function Analyses of Prostaglandin E2 Receptor Subtypes 1 and 3
(2012-11-21)
Prostaglandin E2 (PGE2) is a lipid autacoid, which is an oxidative metabolite of arachidonic acid synthesized by cyclooxygenase and prostaglandin E synthases. PGE2 is proposed to mediate in part the pathophysiology of ...