Browsing Electronic Theses and Dissertations by Department "Biomedical Informatics"
Now showing items 81-100 of 131
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(2013-04-18)Department: Biomedical InformaticsExisting research on evaluating patients’ interests has focused on user surveys, which encounter problems such as high financial and time costs as well as a low user participation rate. To address these problems, this study ...
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(2008-12-15)Department: Biomedical InformaticsThe evaluation of the literature is an increasingly integral part of biomedical research. Clinicians, researchers, librarians, and others routinely use the literature to answer questions for clinical care and research. ...
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Improving Provider-to-Provider Communication: Evaluation of a Computerized Inpatient Sign-out Tool (2007-09-13)Department: Biomedical InformaticsPhysicians’ use of a computerized inpatient sign-out tool has been shown to reduce the risk of preventable adverse events. The researcher evaluated sign-out software usage at Vanderbilt University Medical Center in order ...
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(2007-07-24)Department: Biomedical InformaticsRecent advances in single nucleotide polymorphism (SNP) genotyping techniques, public databases, and genomic knowledge via the Human Genome Project and the Haplotype Mapping project (HapMap) allow for true genome-wide ...
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(2008-06-06)Department: Biomedical InformaticsThis Master’s Thesis project had as its objectives: (1) to optimize algorithms for solvent-accessible surface area (SASA) approximation to develop an environment free energy knowledge-based potential; and, (2) to assess ...
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(2018-11-29)Department: Biomedical InformaticsImplementing machine learning in healthcare has increased in the past years. Representing clinical data is the Crux of machine learning. Learning informative features can improve the trained models’ performance. This ...
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(2017-04-17)Department: Biomedical InformaticsPatient care is complex and imperfect. Understanding and improving patient care requires clinical datasets and scientific methodology. We designed a set of methods to characterize the state of patient care and identify ...
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(2015-08-06)Department: Biomedical InformaticsDissertation under the direction of Dr. Christoph U. Lehmann Health care providers prescribe medications to treat disease or maintain health of their patients. In an inpatient environment, once a medication order has been ...
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(2020-01-15)Department: Biomedical InformaticsCharacterization of signal execution dynamics within complex biochemical networks is highly challenging but necessary to understand how cells process signals and commit to a biological phenotype. Mechanistic interpretation ...
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(2011-09-14)Department: Biomedical InformaticsThis PhD Dissertation project had as its objectives: (1) to develop MIASMA, a potentially open-source Medical Informatics Application for Systematic Microbiological Alerts that uses recently developed methods (e.g., from ...
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(2018-04-04)Department: Biomedical InformaticsOur research focused on the study of clinical workflow using an iterative mixed-methods approach that integrated data analytics with qualitative observations of people, processes and use of technologies. This methodology ...
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(2005-12-16)Department: Biomedical InformaticsIn light of the growing scarcity of livers available for transplantation, careful decisions must be made in organ allocation. The current standard of care for transplant decision making is the use of clinical judgment, ...
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(2020-11-16)Department: Biomedical InformaticsMedication adherence is a complex set of time-varying behaviors—filling, ingesting, and refilling medication at the right time and in the right manner—necessary to effective pharmacotherapy. Proper methods of quantifying ...
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(2009-12-11)Department: Biomedical InformaticsThe focus of my research was to develop several novel computational techniques for discovering informative patterns and complex relationships in biomedical data. First, an efficient, heuristic method was developed to ...
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(2007-10-04)Department: Biomedical InformaticsIn health care, a widespread crisis of emergency department crowding has arisen from increasing patient demand and diminishing bed capacity. Predictable fluctuations in patient demand suggest that dynamic resource ...
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(2016-08-05)Department: Biomedical InformaticsProteomics allows us to see post-translational modifications and expression patterns that we cannot see with genomics and transcriptomics alone. By itself, proteomics has limited sensitivity to detect genetic variation ...
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(2016-04-11)Department: Biomedical InformaticsThesis under the direction of Dr. Jeremy L. Warner The practice of oncology increasingly relies on genetic information from tumors to determine diagnosis, prognosis and therapy. These tumor molecular profiling reports are ...
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(2017-05-30)Department: Biomedical InformaticsPathway exploration can support clinical research efforts and shared decision making between providers, patients, and their families. In this work, we extend the Pathfinder temporal abstraction method and developed a ...
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(2017-04-05)Department: Biomedical InformaticsIntegrating personalized risk predictions into clinical decision support requires well-calibrated models, yet model accuracy deteriorates as patient populations shift. Understanding the influence of modeling methods on ...
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(2016-06-15)Department: Biomedical InformaticsColorectal Cancer (CRC) remains a leading cause of cancer-related mortality in the United States. A key therapeutic dilemma in the treatment of CRC is whether patients with stage II and stage III disease require adjuvant ...