Browsing Electronic Theses and Dissertations by Department "Biomedical Informatics"
Now showing items 101-120 of 131
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(2016-11-21)Department: Biomedical InformaticsBreast cancer patients suffer from the symptoms of their illness as well as from burden of treatment imposed by their care. Patients with high levels of burden tend to be less compliant with treatment plans resulting in ...
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(2013-12-16)Department: Biomedical InformaticsCoronary artery disease (CAD) is the leading cause of death worldwide. Acute coronary syndromes (ACS), a subset of CAD, account for 1.4 million hospitalizations $165 billion in costs in the United States alone. A major ...
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(2012-05-15)Department: Biomedical InformaticsSpectral counting has become a widely used approach for comparing protein abundance in label-free shotgun proteomics. However, when analyzing complex samples, the ambiguity of matching between peptides and proteins greatly ...
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(2018-11-21)Department: Biomedical InformaticsCirrhosis, a late stage of chronic liver damage where scarring replaces hepatic tissue, carries significant morbidity and mortality. The prevalence is estimated between 400,000 and 3,000,000 persons in the United States, ...
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(2018-10-30)Department: Biomedical InformaticsEarly data suggests that cancer providers who are more tightly connected have better clinical outcomes and lower costs. Many current methods to describe and measure provider connectivity are relatively simple, yet not easy ...
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(2019-10-17)Department: Biomedical InformaticsRisk prediction models are increasingly employed in clinical environments to support population health management, quality assessment, and clinical decision support tools directly integrated with electronic health records. ...
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(2021-03-25)Department: Biomedical InformaticsBeginning in the 2000s, electronic health record (EHR) systems have collected large amounts of clinical data. To leverage EHR data for drug studies, researchers have developed powerful computational methods. However, these ...
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(2015-08-03)Department: Biomedical InformaticsMonitoring quality metrics continuously in breast cancer care can help healthcare providers and organizations engage with patients, advance the delivery of care, and tackle financial challenges. In this work, we develop ...
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(2022-10-10)Department: Biomedical InformaticsCOVID-19 survivors are at risk for long-term health effects, but assessing the sequelae of COVID-19 at large scales is challenging. High-throughput methods to efficiently identify new medical problems arising after acute ...
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(2021-08-05)Department: Biomedical InformaticsMany predictive models deployed in healthcare settings abstract away or ignore the temporal nature of disease and the healthcare process. Those that do model time face a myriad of development decisions. One such decision ...
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(2014-11-14)Department: Biomedical InformaticsFilamentous fungi produce diverse secondary metabolites (SMs) essential to their ecology and adaptation. Although each SM is typically produced by only a handful of species, SM production is coordinated with developmental ...
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(2017-07-20)Department: Biomedical InformaticsFilamentous fungi produce a diverse array of secondary metabolites (SMs) that play ecological roles in defense, virulence, and inter- and intra-species communication. Fungal SMs have both deleterious and beneficial impacts ...
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(2021-05-12)Department: Biomedical InformaticsDespite widespread adoption of electronic health records (EHRs), medication errors persist. Modern clinical decision support (CDS) systems to prevent medication errors still rely on simple alerts, such as those pertaining ...
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(2005-12-14)Department: Biomedical InformaticsDealing with a cancer diagnosis and cancer treatment involves communication among clinicians, patients, families, friends and others affected by the illness. The hypothesis for this research is that an informatics system ...
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(2023-11-27)Department: Biomedical InformaticsAir pollution is a common irritant trigger for asthma exacerbations. Self-management is pivotal in asthma treatment and encompasses symptom tracking, trigger awareness, medication adherence, and seeking healthcare when ...
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The systematic ascertainment of structured family health information using an online patient portal (2012-07-30)Department: Biomedical InformaticsFamily Health Information (FHI) helps identify individuals who are at increased risk for adverse health conditions due to inherited genetic or environmental predisposition. Appropriate stratification of patients based on ...
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(2010-05-25)Department: Biomedical InformaticsTo diagnose and treat patients, clinicians concern themselves with a complex set of events. They need to know when, how long, and in what sequence certain events occur. An automated means of extracting temporal meaning in ...
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(2018-07-26)Department: Biomedical InformaticsAltered kinase signaling is one of the hallmarks of cancer that has previously been studied at the genomic and transcriptomic level. However, phosphoproteomic data are an increasingly popular way to study global cell ...
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(2022-01-06)Department: Biomedical InformaticsLearning health systems have the capability to conduct systematic evaluation of medical interventions. Systematic evaluation of medical interventions with electronic health record data requires an accurate and complete ...
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(2010-08-02)Department: Biomedical InformaticsIntensive insulin therapy (IIT), a nurse-driven protocol combining frequent blood glucose testing and insulin administration to tightly control blood glucose, became the standard of critical care following a 2001 study. ...