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Reactive Arial-based Antitachycardia Pacing Therapy Reduces Atrial Tachyarrhthmias
(PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY, 2019-07)
Background Reactive atrial-based antitachycardia pacing (rATP) aims to terminate atrial tachyarrhythmia/atrial fibrillation (AT/AF) episodes when they spontaneously organize to atrial flutter or atrial tachycardia; however, ...
Insulin Resistance Exacerbates Genetic Predisposition to Nonalcoholic Fatty Liver Disease in Individuals Without Diabetes
(HEPATOLOGY COMMUNICATIONS, 2019-07)
The accumulation of excess fat in the liver (hepatic steatosis) in the absence of heavy alcohol consumption causes nonalcoholic fatty liver disease (NAFLD), which has become a global epidemic. Identifying metabolic risk ...
Novel HLA Class I Alleles Outside the Extended DR3 Haplotype Are Protective against Autoimmune Hepatitis
(Clinical and Translational Gastroenterology, 2019-06-18)
Abstract
INTRODUCTION: HLA class II allele, DRB1*03:01, is the most common genetic risk factor for autoimmune hepatitis (AIH), but other unrecognized HLA related risks exist.
METHODS: We compared the HLA class I (A, ...
Longer Breastfeeding Associated with Childhood Anemia in Rural South-Eastern Nigeria
(International Journal of Pedicatrics, 2019)
Introduction. Child mortality rate in sub-Saharan Africa is 29 times higher than that in industrialized countries. Anemia is one of the preventable causes of child morbidity. During a humanitarian medical mission in rural ...
A gene co-expression network-based analysis of multiple brain tissues reveals novel genes and molecular pathways underlying major depression
(PLOS Genetics, 2019-07)
Major depression is a common and severe psychiatric disorder with a highly polygenic genetic architecture. Genome-wide association studies have successfully identified multiple independent genetic loci that harbour variants ...