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Enteral Autonomy and Days Off Parenteral Support With Teduglutide Treatment for Short Bowel Syndrome in the STEPS Trials
(Journal of Parenteral and Enteral Nutrition, 2020-05)
Background Teduglutide response, in terms of parenteral support (PS) volume reduction, is associated with specific disease characteristics among adults with short bowel syndrome-associated intestinal failure (SBS-IF). ...
PEGylated PLGA Nanoparticle Delivery of Eggmanone for T Cell Modulation: Applications in Rheumatic Autoimmunity
(International Journal of Nanomedicine, 2020)
Background: Helper T cell activity is dysregulated in a number of diseases including those associated with rheumatic autoimmunity. Treatment options are limited and usually consist of systemic immune suppression, resulting ...
Impact of liver tumour burden, alkaline phosphatase elevation, and target lesion size on treatment outcomes with Lu-177-Dotatate: an analysis of the NETTER-1 study
(European Journal of Nuclear Medicine and Molecular Imaging, 2020-09)
Purpose To assess the impact of baseline liver tumour burden, alkaline phosphatase (ALP) elevation, and target lesion size on treatment outcomes with Lu-177-Dotatate. Methods In the phase 3 NETTER-1 trial, patients with ...
Sex hormone exposure and reproductive factors in pulmonary arterial hypertension: a case-control study
(Pulmonary Circulation, 2020-01)
Pulmonary arterial hypertension (PAH) is a sexually dimorphic disease that for unknown reasons affects women more than men. The role of estrogens, both endogenous and exogenous, and reproductive factors in this female ...
Reverse Cardio-Oncology: Cancer Development in Patients With Cardiovascular Disease
(Journal of the American Heart Association, 2020-01-21)
International Consortium for Health Outcomes Measurement (ICHOM): Standardized Patient-Centered Outcomes Measurement Set for Heart Failure Patients
(JACC-Heart Failure, 2020-03)
Whereas multiple national, international, and trial registries for heart failure have been created, international standards for clinical assessment and outcome measurement do not currently exist. The working group's objective ...
snapMRF: GPU-accelerated magnetic resonance fingerprinting dictionary generation and matching using extended phase graphs
(Magnetic Resonance Imaging, 2020-02)
Purpose:: Magnetic resonance fingerprinting (MRF) is a state-of-the-art quantitative MRI technique with a computationally demanding reconstruction process, the accuracy of which depends on the accuracy of the signal model ...
A World of Collaboration in Sports Medicine: the 2020 American Medical Society for Sports Medicine issue
(British Journal of Sports Medicine, 2020-02)
World Health Organization's Growth Reference Overestimates the Prevalence of Severe Malnutrition in Children with Sickle Cell Anemia in Africa
(Journal of Clinical Medicine, 2020-01)
Anthropometric indices are widely used to assess the health and nutritional status of children. We tested the hypothesis that the 2007 World Health Organization (WHO) reference for assessment of malnutrition in children ...
Identification and validation of biomarkers of persistent acute kidney injury: the RUBY study
(Intensive Care Medicine, 2020-02)
Purpose The aim of the RUBY study was to evaluate novel candidate biomarkers to enable prediction of persistence of renal dysfunction as well as further understand potential mechanisms of kidney tissue damage and repair ...