Now showing items 1-10 of 194
Progression and Pathology of Traumatic Optic Neuropathy From Repeated Primary Blast Exposure
(FRONTIERS IN NEUROSCIENCE, 2019-07-11)
Indirect traumatic optic neuropathy (ITON) is a condition that is often associated with traumatic brain injury and can result in significant vision loss due to degeneration of retinal ganglion cell (RGC) axons at the time ...
Patient Registries in Idiopathic Pulmonary Fibrosis
(American Journal of Respiratory and Critical Care Medicine, 2019-07-15)
Over the past decade, several large registries of patients with idiopathic pulmonary fibrosis (IPF) have been established. These registries are collecting a wealth of longitudinal data on thousands of patients with this ...
Reactive Arial-based Antitachycardia Pacing Therapy Reduces Atrial Tachyarrhthmias
(PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY, 2019-07)
Background Reactive atrial-based antitachycardia pacing (rATP) aims to terminate atrial tachyarrhythmia/atrial fibrillation (AT/AF) episodes when they spontaneously organize to atrial flutter or atrial tachycardia; however, ...
Key Mechanisms by Which Post-ICU Activities can Improve in-ICU Care: Results of the International THRIVE Collaboratives
(INTENSIVE CARE MEDICINE, 2019-07)
ObjectiveTo identify the key mechanisms that clinicians perceive improve care in the intensive care unit (ICU), as a result of their involvement in post-ICU programs.MethodsQualitative inquiry via focus groups and interviews ...
Oral Tresprostinil in Transition or as Add-on Therapy in Pediatric Pulmonary Arterial hypertension
(Pulmonary Circulation, 2019-07-12)
Treprostinil, a prostacyclin analogue, is approved for the treatment of pulmonary arterial hypertension (PAH) in adults. Transition from parenteral to oral treprostinil has been successfully accomplished in adults with PAH ...
Epidemiological Characterists of Advanced Hepatocellular Cardinoma in the Northern Region of Vietnam
(Cancer Control, 2019-07-10)
Epidemiological characteristics of hepatocellular carcinoma (HCC) in Southern Vietnam has been well reported as in Globocan 2018 while data from the North has still not been fully presented. Therefore, we conducted this ...
The Consortium of Metabolomics Studies (COMETS): Metabolomics in 47 Prospective Cohort Studies
(AMERICAN JOURNAL OF EPIDEMIOLOGY, 2019-06)
The Consortium of Metabolomics Studies (COMETS) was established in 2014 to facilitate large-scale collaborative research on the human metabolome and its relationship with disease etiology, diagnosis, and prognosis. COMETS ...
The CDK7 Inhibitor THZ1 Alters RNA Polymerase Dynamics at the 5 ' and 3 ' Ends of Genes
(NUCLEIC ACIDS RESEARCH, 2019-05)
The t(8;21) is one of the most frequent chromosomal translocations associated with acute myeloid leukemia (AML). We found that t(8; 21) AML were extremely sensitive to THZ1, which triggered apoptosis after only 4 h. We ...
Global Patterns in Monthly Activity of Influenza Virus, Respiratory Syncytial Virus, Parainfluenza Virus, and Metapneumovirus: a Systematic Analysis
(LANCET GLOBAL HEALTH, 2019-08)
Background Influenza virus, respiratory syncytial virus, parainfluenza virus, and metapneumovirus are the most common viruses associated with acute lower respiratory infections in young children (<5 years) and older people ...
Universal Influenza Vaccination Among Healthcare Personnel: Yes We Should
(OPEN FORUM INFECTIOUS DISEASES, 2019-04)