Now showing items 1-4 of 4
Oral Tresprostinil in Transition or as Add-on Therapy in Pediatric Pulmonary Arterial hypertension
(Pulmonary Circulation, 2019-07-12)
Treprostinil, a prostacyclin analogue, is approved for the treatment of pulmonary arterial hypertension (PAH) in adults. Transition from parenteral to oral treprostinil has been successfully accomplished in adults with PAH ...
Low-grade albuminuria in pulmonary arterial hypertension
(PULMONARY CIRCULATION, 2019-06)
Low-grade albuminuria, determined by the urinary albumin to creatinine ratio, has been linked to systemic vascular dysfunction and is associated with cardiovascular mortality. Pulmonary arterial hypertension is related to ...
A multifaceted investigation into molecular associations of chronic thromboembolic pulmonary hypertension pathogenesis
(JRSM Cardiovascular Disease, 2020-02)
Purpose Chronic thromboembolic pulmonary hypertension is characterized by incomplete thrombus resolution following acute pulmonary embolism, leading to pulmonary hypertension and right ventricular dysfunction. Conditions ...
Sex hormone exposure and reproductive factors in pulmonary arterial hypertension: a case-control study
(Pulmonary Circulation, 2020-01)
Pulmonary arterial hypertension (PAH) is a sexually dimorphic disease that for unknown reasons affects women more than men. The role of estrogens, both endogenous and exogenous, and reproductive factors in this female ...