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Reactive Arial-based Antitachycardia Pacing Therapy Reduces Atrial Tachyarrhthmias
(PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY, 2019-07)
Background Reactive atrial-based antitachycardia pacing (rATP) aims to terminate atrial tachyarrhythmia/atrial fibrillation (AT/AF) episodes when they spontaneously organize to atrial flutter or atrial tachycardia; however, ...
A gene co-expression network-based analysis of multiple brain tissues reveals novel genes and molecular pathways underlying major depression
(PLOS Genetics, 2019-07)
Major depression is a common and severe psychiatric disorder with a highly polygenic genetic architecture. Genome-wide association studies have successfully identified multiple independent genetic loci that harbour variants ...
Insulin Resistance Exacerbates Genetic Predisposition to Nonalcoholic Fatty Liver Disease in Individuals Without Diabetes
(HEPATOLOGY COMMUNICATIONS, 2019-07)
The accumulation of excess fat in the liver (hepatic steatosis) in the absence of heavy alcohol consumption causes nonalcoholic fatty liver disease (NAFLD), which has become a global epidemic. Identifying metabolic risk ...
Novel HLA Class I Alleles Outside the Extended DR3 Haplotype Are Protective against Autoimmune Hepatitis
(Clinical and Translational Gastroenterology, 2019-06-18)
Abstract
INTRODUCTION: HLA class II allele, DRB1*03:01, is the most common genetic risk factor for autoimmune hepatitis (AIH), but other unrecognized HLA related risks exist.
METHODS: We compared the HLA class I (A, ...
Longer Breastfeeding Associated with Childhood Anemia in Rural South-Eastern Nigeria
(International Journal of Pedicatrics, 2019)
Introduction. Child mortality rate in sub-Saharan Africa is 29 times higher than that in industrialized countries. Anemia is one of the preventable causes of child morbidity. During a humanitarian medical mission in rural ...