Browsing Vanderbilt University Medical Center by Title
Now showing items 6-25 of 315
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(PLOS GENETICS, 2019-06)Dendrite growth is constrained by a self-avoidance response that induces retraction but the downstream pathways that balance these opposing mechanisms are unknown. We have proposed that the diffusible cue UNC-6(Netrin) is ...
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(NATURE COMMUNICATIONS, 2019-07-10)TFF1, a secreted protein, plays an essential role in keeping the integrity of gastric mucosa and its barrier function. Loss of TFF1 expression in the TFF1-knockout (KO) mouse leads to a pro-inflammatory phenotype with a ...
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(Nutrition & Diabetes, 2019-09-02)Background: Aerobic exercise training is known to have beneficial effects on whole-body glucose metabolism in people with type 2 diabetes (T2D). The responses of the liver to such training are less well understood. The ...
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(Genome Biology, 2019-04-26)BackgroundAfrica is the origin of modern humans within the past 300 thousand years. To infer the complex demographic history of African populations and adaptation to diverse environments, we sequenced the genomes of 92 ...
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(2019-07)Background. Rates of influenza hospitalizations differ by age, but few data are available regarding differences in laboratory-confirmed rates among adults aged >= 65 years. Methods. We evaluated age-related differences ...
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(Infectious Diseases and Therapy, 2019-09)Introduction Agreement between available procalcitonin (PCT) assays is unclear. We sought to compare concordance between Roche and bioMerieux PCT assays using pediatric samples. Methods We evaluated 213 plasma samples from ...
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(Molecules, 2022-12-09)Although 3-aminopropyl functionalized magnesium phyllosilicate nanoparticles (hereafter aminoclay nanoparticles, ACNs) are well-known nanomaterials employed as drug carriers, their effects on immune cells remain unclear. ...
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(Antioxidants, 2020-01)Gastric cancer is the third main cause of cancerous tumors in humans in Chile. It is well-accepted that a diet rich in antioxidant plants could help in fighting cancer. Blueberry is a fruit crop with a high content of ...
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(eLife, 2019-03-27)Immune activated T lymphocytes modulate the activity of key metabolic pathways to support the transcriptional reprograming and reshaping of cell proteomes that permits effector T cell differentiation. The present study ...
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(Cancer Control, 2019-07-19)Anxiety, a condition which is commonly found in patients with cancer, has negative impacts on their quality of life and treatment outcome. This study aimed to determine the level of anxiety in patients with cancer and ...
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(Journal of Pharmacology and Experimental Therapeutics, 2019-06-01)Active transport by renal proximal tubules plays a significant role in drug disposition. During drug development, estimates of renal excretion are essential to dose determination. Kidney bioreactors that reproduce physiologic ...
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(Kidney International Reports, 2019-07)Introduction: High dietary acid load and metabolic acidosis are associated with an accelerated decline in kidney function and may contribute to the observed heterogeneity in end-stage renal disease (ESRD) risk according ...
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(Journal of the American Heart Association, 2019-08-06)Background-Subtle reductions in cardiac output relate to lower cerebral blood flow, especially in regions where Alzheimer's disease pathology first develops. Apolipoprotein E (APOE)-epsilon 4 is a genetic susceptibility ...
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(JAMA DERMATOLOGY, 2019-05)IMPORTANCE The well-being and development of children is strongly influenced by parents' physical and psychosocial health. Data from small, clinic-based studies suggest that sleep loss may be common in parents of children ...
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(BMJ-British Medical Journal, 2020-02-05)OBJECTIVE To assess whether an association exists between financial links to the indoor tanning industry and conclusions of indoor tanning literature. DESIGN Systematic review. DATA SOURCE PubMed, Embase, ...
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(JAMA Network Open, 2019-04)IMPORTANCE Asia is home to the largest diabetic populations in the world. However, limited studies have quantified the association of diabetes with all-cause and cause-specific mortality in Asian populations. OBJECTIVES ...
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(JAMA Network Open, 2019-11)IMPORTANCE Despite the rapidly changing policy environment regarding substance use during pregnancy, information is lacking on the association of state policies with neonatal abstinence syndrome (NAS). OBJECTIVE To ...
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(JAMA Network Open, 2019-05)IMPORTANCE The American Heart Association 2020 Strategic Impact Goals target an improvement in overall cardiovascular health, as assessed by 7 health metrics (smoking, body weight, physical activity, diet, plasma glucose ...
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(BMJ Open, 2019-10)Objective To explore how three indicators of social capital (ie, group membership, social support and cognitive social capital and specific types within each type) are associated with infant birth weight. Study design ...
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(Clinical Interventions in Aging, 2019)Purpose: Recent studies have found associations of increased brain amyloid beta (A beta) accumulation and several abnormal sleep-wake patterns, including shorter latency and increased fragmentation in preclinical Alzheimer's ...