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Viral flight data recorder for systems biology applications
(Vanderbilt University, 2008-08-13)
The paper briefly describes the construction of self organizing nanoparticles that can be designed to detect and record arbitrary intracellular events. The basic design captures nucleic acids. The design utilizes a single ...
Nanoscale dolmen structure exhibiting a tunable Fano resonance
(Vanderbilt University. Dept. of Physics and Astronomy, 2016-05-02)
A Fano resonance is an asymmetric, resonant scattering phenomenon which occurs in a multitude of fields, such as atomic physics, nuclear physics, nonlinear optics, and nanophotonics. The Fano resonance is a many-particle ...
Thermal fabrication of gold nanocages
(Vanderbilt University. Department of Physics and Astronomy, 2011-04-11)
The purpose of this research project was to test and characterize a new method
for gold nanoparticle production. The main idea was based on the preliminary
observations made in earlier work, which had suggested that small ...
Designer nanoparticles to detect and treat disease
(2009-12-02)
Conjugation of targeting, imaging and drug molecules to nanoparticles has been a developing area of interest over the last 10-15 years. Although great strides have been made, characterization and activity of functionalized ...
Development of a Nanoparticle-Based System for Imaging and Targeted Therapeutic Delivery to Tumor Cells
(2006-02-06)
Selective targeting of damaged or diseased cells is a concept with great potential to revolutionize the efficacy of systemically administered agents. Successful targeting preferentially delivers imaging agents and/or ...
Electrophoretic separations of monolayer protected clusters
(2009-07-29)
The determination of electrophoretic properties and the size separation of monolayer protected clusters (MPCs) are presented in this thesis. MPCs are metallic nanoparticles encapsulated in a protecting thiolate monolayer. ...
Nanoscale Gold for Enhanced Protein Electrochemistry, Ebolavirus Immunosensors, and In Vivo Distribution Measurements
(2009-11-02)
Different applications using gold at the nanoscale level are discussed in this dissertation. The first section includes relevant background into nanoparticles, specifically, monolayer protected gold clusters (MPC), and ...
Design and Optimization of Novel Hybrid PLGA and Endosomolytic Polymer Nanoparticles for siRNA Delivery and Use as a Treatment for Osteoarthritis
(2022-03-27)
Small interfering RNA (siRNA) has emerged as a potent regulator of gene expression,
with the potential to treat a variety of previously “undruggable” diseases. However, its clinical translation has been limited due to short ...
A literature review of nanoparticle addition to concrete for nuclear applications
(2018-05-16)
Concrete dry casks are currently the primary storage solution for spent nuclear fuel in the United States. These above-ground storage chambers may be used for a century or more, and are subject to degradation by environmental ...
Synthetic and Biological Studies of Hemiketal E2 & Gaining Molecular Insight on the Synthesis of Nanoparticles
(2023-01-09)
Since the discovery that nonsteroidal anti-inflammatory drugs (NSAIDs) prevent pain, swelling, and inflammation by inhibiting the enzymes cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2), there has been interest in ...