Browsing by Subject "macrophages"
Now showing items 1-9 of 9
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(International Journal of Moledular Sciences, 2019-06-01)The PI3K/Akt pathway plays a crucial role in the survival, proliferation, and migration of macrophages, which may impact the development of atherosclerosis. Changes in Akt isoforms or modulation of the Akt activity levels ...
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(International Journal of Molecular Sciences, 2019-06-01)The PI3K/Akt pathway plays a crucial role in the survival, proliferation, and migration of macrophages, which may impact the development of atherosclerosis. Changes in Akt isoforms or modulation of the Akt activity levels ...
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(2018-11-15)Department: Biomedical EngineeringAdvanced organic chemistry allows for design of unique nanocarriers that have specific functions tailored for in vivo applications, such as decorating with mannose to target tumor-associated macrophages for immunotherapy ...
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(2012-12-03)Department: Biomedical EngineeringMacrophages have been proposed as a potential therapeutic target because of their central role in the progression of a number of debilitating diseases, such as cancer and cardiovascular diseases. However, macrophages are ...
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(2012-03-29)Department: Molecular Physiology and BiophysicsObesity is closely linked to many metabolic diseases such as insulin resistance (IR), type 2 diabetes mellitus and cardiovascular disease. In the past decade, it has been established that immune cells are recruited to ...
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(2023-03-24)Department: Chemical EngineeringThe majority of breast cancer patients receive radiation therapy. Although this treatment improves overall outcomes, patients with triple negative breast cancer (TNBC) have a significantly higher risk of distant and ...
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(2016-03-30)Department: Cell and Developmental BiologySpasmolytic polypeptide-expression metaplasia (SPEM) develops in the atrophic stomach and progresses to an intestinalized SPEM in the setting of inflammation. Different immune deficient mouse models determined that T-cells, ...
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(2016-02-19)Department: Cancer BiologyNuclear factor κ-light chain enhancer of activated B cells (NF-κB) is a transcription factor that can be activated through canonical or non-canonical signaling pathways, and activation of both pathways has been observed ...
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(2019-03)The gastric bacterium Helicobacter pylori causes a persistent infection that is directly responsible for gastric ulcers and gastric cancer in some patients and protective against allergic and other immunological disorders ...