Browsing by Subject "enteric nervous system"
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Enteric nervous system deficits in the ganglionated bowel of Hirschsprung mouse models and patients. (2014-11-26)Department: Human GeneticsHirschsprung disease, or congenital absence of ganglia in the distal intestine, occurs in approximately every 1 in 5000 live births. Although HSCR patients have the aganglionic portion of their colon removed, many suffer ...
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(2011-02-15)Department: Human GeneticsHirschsprung disease (HSCR) is characterized by a lack of enteric ganglia in a variable portion of the distal bowel. The complex inheritance pattern of this disorder has led researchers to focus on genetic effects other ...