Browsing by Subject "endothelium"
Now showing items 1-5 of 5
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(Arteriosclerosis Thrombosis and Vascular Biology, 2019-07)Objective- Activation of coagulation FXI (factor XI) by FXIIa (activated factor XII) is a prothrombotic process. The endothelium is known to play an antithrombotic role by limiting thrombin generation and platelet activation. ...
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(2010-09-21)Department: Cell and Developmental BiologyThis dissertation project was aimed at elucidating cellular and molecular responses to myocardial infarction. Our work identified canonical wnt signaling as a molecular pathway that is induced in the healing (granulation ...
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(Frontiers in Neurology, 2019-05-01)Background: Asphyxia is the most common cause of brain damage in newborns. Substantial evidence indicates that leukocyte recruitment in the cerebral vasculature during asphyxia contributes to this damage. We tested the ...
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(2018-07-22)Department: Molecular Physiology and BiophysicsSkeletal muscle insulin resistance is a state of metabolic dysfunction that increases the risk of developing Type 2 diabetes and cardiovascular disease. Despite decades of research into potential myocellular defects, the ...
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(2018-08-02)Department: Molecular Physiology and BiophysicsIt is increasingly evident that inflammation and immune activation occur in hypertension, by mechanisms that are poorly understood. Monocytes play an important role in hypertension. Circulating monocytes in humans exist ...