Browsing by Subject "drug resistance"
Now showing items 1-2 of 2
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(2014-11-24)Department: Chemical and Physical BiologyIntratumor heterogeneity underlies the failure of targeted cancer therapy. The origins of this phenotypic variability derive from the coincident contributions of genetic, non-genetic, and stochastic factors. However, few ...
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(2021-03-29)Department: Cancer BiologyBone is a common site of metastasis for advanced breast, prostate, and lung cancer. Most patients with skeletal metastases develop tumor-induced bone disease (TIBD), which is characterized by a vicious cycle of tumor growth ...