Browsing by Subject "cytoskeleton"

Now showing items 1-6 of 6

    • Characterization of CytLEK1 as a Novel Regulator of the LIS1 Pathway 
      Soukoulis, Victor (2005-03-25)
      Department: Cell and Developmental Biology
      LIS1 and NudE(L) are partner proteins in a conserved pathway regulating the function of dynein and microtubules. Members of the LIS1 pathway play a critical role in fundamental cellular processes, such as differentiation, ...
    • Dynamics and Regulation of Microtubule Minus Ends 
      Strothman, Claire E; 0000-0001-7849-0626 (2021-06-08)
      Department: Cell & Developmental Biology
      Dynamics and Regulation of Microtubule Minus Ends Microtubules are an integral part of the cytoskeletal system in cells and serve essential roles in cell division, intracellular transport, and morphogenesis. Microtubules ...
    • Function and regulation of the CLASP-dependent microtubule array at the Golgi 
      Miller, Paul Myron (2010-08-02)
      Department: Cell and Developmental Biology
      This project provides a detailed characterization of the CLASP-dependent microtubule array at the Golgi in terms of function and regulation. First, I briefly outline the process of MT nucleation at the Golgi and highlight ...
    • INVESTIGATING THE ROLE OF MYOSIN-GENERATED FORCE IN SHAPING CELL MORPHOLOGY 
      Fitz, Gillian; 0000-0002-5995-6918 (2023-11-16)
      Department: Cell & Developmental Biology
      Actin-based protrusions are found on the surface of all eukaryotic cells, where they support diverse biological activities essential for life. Models of protrusion growth hypothesize that actin filament assembly provides ...
    • Mechanisms of BAR Protein Function in Brush Border Assembly 
      Postema, Meagan Marie (2019-09-17)
      Department: Cell and Developmental Biology
      The intestinal brush border lines the apical surface of enterocytes and is composed of thousands of actin-supported protrusions called microvilli, which extend into the intestinal lumen. Microvilli function to increase ...
    • Non-redundant functions of the mouse Ssrp1 and Pfdn1 genes revealed by gene targeting and gene entrapment 
      Cao, Shang (2005-12-13)
      Department: Microbiology and Immunology
      NON-REDUNDANT FUNCTIONS OF THE MOUSE SSRP1 AND PFDN1 GENES REVEALED BY GENE TARGETING AND GENE ENTRAPMENT SHANG CAO Dissertation under the direction of Professor Henry Earl Ruley In the post-genome era, gene targeting ...