Browsing by Subject "coronavirus"

Now showing items 1-9 of 9

    • Analysis of coronavirus nonstructructural proteins in virus-indued membrane modifications 
      Beachboard, Dia Chenelle (2015-02-11)
      Department: Microbiology and Immunology
      Coronaviruses are positive-sense RNA viruses that cause significant diseases in humans. Severe Acute Respiratory Syndrome coronavirus (SARS-CoV) caused a pandemic in 2002-2003, and Middle East Respiratory Syndrome coronavirus ...
    • Analysis of Papain-like Protease Mediated Processing and Roles of the Cleavage Products in Coronavirus Replication 
      Gadlage, Mark Jacob (2010-03-02)
      Department: Microbiology and Immunology
      Coronaviruses belong to a family of enveloped, positive-strand RNA viruses that cause a multitude of devastating diseases in both animals and humans. Like other positive-strand RNA viruses, coronaviruses utilize several ...
    • Defining the determinants and outcomes of coronavirus recombination 
      Gribble, Jennifer; 0000-0003-0815-5798 (2022-01-04)
      Department: Microbe-Host Interactions
      Coronaviruses (CoVs) are a genetically diverse group of positive-sense single-stranded RNA viruses containing the largest known genome of any RNA virus, >30 kb, and responsible for the current COVID-19 pandemic (SARS-CoV-2). ...
    • Efficiently Mining the B cell Repertoire for Cross-Reactive Coronavirus Antibodies 
      Wall, Steven Craig; 0000-0002-1220-7020 (2024-03-20)
      Department: Microbe-Host Interactions
      Coronaviruses (CoVs) are single-stranded, positive-sense RNA viruses that infect a wide variety of species including birds, reptiles, and mammals. SARS-CoV-2 is only the latest coronavirus to jump from animals into humans ...
    • Episode 076 - Bryan Alexander 
      Bruff, Derek (Vanderbilt University, 2020-03-30)
      In late March 2020, most institutions of higher education in the US and around the world have closed their campuses in response to the coronavirus pandemic, and in most cases those institutions have shifted the entirety ...
    • Investigating Nucleoside Analogue Inhibition of Coronavirus Replication 
      Agostini, Maria (2019-10-17)
      Department: Microbiology and Immunology
      Emerging viruses, such as coronaviruses (CoVs), continue to pose a threat to human health, and few countermeasures have been approved to treat these infections. Two CoVs have emerged to cause severe disease in humans within ...
    • Investigation of Host Proteostasis Dependencies to Inhibit RNA Virus Infection 
      Almasy, Katherine Mandy; 0000-0002-6747-4249 (2022-06-06)
      Department: Chemistry
      Viral life cycles are facilitated by protein-protein interactions between viral proteins and the host counterparts to ensure each stage of the replication is productive. These interactions mark potential therapeutic ...
    • Structural and Functional Analysis of Coronavirus Cysteine Protease Nsp5 
      Stobart, Christopher Colin (2013-10-18)
      Department: Microbiology and Immunology
      Coronaviruses (CoV) are positive-strand RNA viruses that encode large replicase polyproteins that are processed by two or three viral proteases to yield intermediate and mature nonstructural proteins (nsps). Nsp5 (3CLpro, ...
    • Tracing adaptive pathways in a proofreading-deficient coronavirus 
      Graepel, Kevin Whittle (2019-05-17)
      Department: Microbiology and Immunology
      Coronaviruses (CoVs) are a family of positive-sense RNA viruses that cause human illnesses ranging from the common cold to severe and lethal respiratory disease. Since 2002, two CoVs (SARS- and MERS-CoV) have emerged as ...