Browsing by Subject "allosteric modulator"
Now showing items 1-3 of 3
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(2010-09-21)Department: PharmacologyThere exist five subtypes of the muscarinic acetylcholine receptor (M1-M5), which are differentially expressed throughout the body and play important roles in numerous physiological processes, including autonomic functions, ...
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(2013-04-15)Department: PharmacologyMetabotropic glutamate receptors (mGluRs) are G protein-coupled receptors that play important roles in the modulation of neurotransmission in the central nervous system (CNS). The eight subtypes of mGluRs are differentially ...
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(2013-12-12)Department: Chemical and Physical BiologyMarineosin A was isolated from a marine sediment-derived actinomycete in 2008. The intriguing biological activity and novel chemical structure warranted completion of the total synthesis of this compound. The model systems ...