Browsing by Subject "G proteins"
Now showing items 1-4 of 4
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(2013-12-09)Department: BiochemistryThe G protein coupled receptor (GPCR) family is comprised of ubiquitous, membrane-bound proteins that are highly conserved in structure, yet varied in their cognate ligand. This allows for regulation of diverse physiological ...
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(2008-07-26)Department: Cell and Developmental BiologyWnt/beta-catenin signaling controls various cell fates in metazoan development and is misregulated in several cancers and developmental disorders. Binding of a Wnt ligand to its transmembrane coreceptors, Frizzled (Fz) ...
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(2016-04-08)Department: PharmacologyGi/o-coupled G-protein coupled receptors (GPCRs) can exert an inhibitory effect on vesicle release through several G-protein driven mechanisms, more than one of which may be concurrently present in individual presynaptic ...
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(2008-05-20)Department: NeuroscienceThe claustrum is a telencephalic grey matter nucleus of unclear structure and function, although it has been recently proposed to be a generator of conscious percepts. Our studies redefine the structural boundaries and ...