Browsing by Subject "Drug Discovery"
Now showing items 1-2 of 2
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(2020-11-17)Department: PharmacologyVolume Regulated Anion Channels (VRACs) encoded by the LRRC8 gene family play critical roles in myriad cellular processes and might represent druggable targets. The dearth of pharmacological compounds available for studying ...
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(2010-08-09)Department: ChemistryThe content described in detail in this dissertation covers natural product guided drug discovery, traditional hit-to-lead medicinal chemistry and advances in total synthesis. The synthesis and biological evaluation of ...