Browsing by Subject "C/EBPbeta"
Now showing items 1-3 of 3
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(2012-05-03)Department: Cancer BiologyC/EBPbeta is a member of a family of basic-leucine zipper transcription factors. It has been shown to be a key regulator of growth and differentiation in the mammary gland. There are three different protein isoforms of ...
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(2010-12-10)Department: Cancer BiologyOverexpression of activated oncogenes such as Ras(V12) in primary cells induces senescence rather than transformation, thus suppressing tumorigenesis. C/EBPbeta is required for Ras(V12)-induced senescence in mouse embryonic ...
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(2010-08-25)Department: Cancer BiologyC/EBPbeta is essential for mammary gland growth and development and has been associated with poor prognosis in breast cancer. Overexpression of C/EBPbeta2 in MCF10A cells, a model of normal mammary epithelial cells, results ...