Browsing by Subject "B cells"
Now showing items 1-6 of 6
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(2019-09-13)Department: Microbiology and ImmunologyNutrient acquisition is important for the survival of all living organisms. Nutrient metals such as iron, is known to play key roles in cellular metabolism, respiration, and both redox and non-redox catalysis. One particularly ...
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(2019-01-17)Department: Microbiology and ImmunologyNew Modes of B lymphocyte Regulation in Autoimmune Disease Christopher Scott Wilson Dissertation under the direction of Professor Daniel J. Moore The deleterious roles that B lymphocytes play in autoimmunity and ...
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(2015-11-09)Department: Microbiology and ImmunologyOverall, these studies examine how peripheral tolerance is governed for autoreactive B lymphocytes that bind the relevant autoAg, insulin. CSR-competent anti-insulin B cells enter mature compartments but are anergic, ...
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Single-cell characterization of antibody responses in coronavirus infection and COVID-19 vaccination (2021-09-08)Department: Molecular Pathology & ImmunologyThe COVID-19 pandemic, caused by the novel coronavirus SARS-CoV-2, has resulted in the illness and death of millions of people worldwide. Although medical countermeasures including monoclonal antibody cocktails and vaccines ...
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(2017-06-19)Department: Microbiology and ImmunologyB cells play a crucial role in adaptive immunity. They perform a multitude of functions including antibody and cytokine production and antigen presentation. The human adaptive immune response would not function effectively ...
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(2016-11-11)Department: Microbiology and ImmunologyThis thesis advances our understanding of circulating B and pTFH cells in untreated chronic HIV+ infection. My studies determined the frequency, phenotype, and functional response to antigen stimulation of pTFH and B cells ...