Browsing by Subject "Alzheimer disease"
Now showing items 1-3 of 3
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(2006-11-01)Department: NeuroscienceCommon diseases with a genetic basis are likely to have a very complex etiology, in which the mapping between genotype and phenotype is far from straightforward. A new comprehensive statistical and computational strategy ...
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(Aging Cell, 2019-08)CpG-related single nucleotide polymorphisms (CGS) have the potential to perturb DNA methylation; however, their effects on Alzheimer disease (AD) risk have not been evaluated systematically. We conducted a genome-wide ...
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(2012-12-07)Department: Human GeneticsLate-onset Alzheimer disease (LOAD) is a complex neurodegenerative disorder with a strong genetic component. APOE is a well-established risk gene for LOAD, and several other genes have also been identified. However, at ...