Browsing by Subject "ATR activator"

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    • ETAA1 promotes genome stability through activation of ATR 
      Bass, Thomas Edwin (2018-11-21)
      Department: Biochemistry
      The ATR kinase controls cell cycle transitions and the DNA damage response. Budding yeast contain three activators of Mec1ATR; however, only TOPBP1 is known to activate ATR in vertebrates. We identified ETAA1 as a replication ...