Browsing by Author "Van Kaer, Luc"
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Park, Hyun Jung; Lee, Sung Won; Song, Jae Geun; Van Kaer, Luc; Cheon, Jae Hee; Lim, Soo-Jeong; Han, Hyo-Kyung; Hong, Seokmann (Molecules, 2022-12-09)Although 3-aminopropyl functionalized magnesium phyllosilicate nanoparticles (hereafter aminoclay nanoparticles, ACNs) are well-known nanomaterials employed as drug carriers, their effects on immune cells remain unclear. ...
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Imai, Takashi; Suzue, Kazutomo; Ngo-Thanh, Ha; Ono, Suguri; Orita, Wakako; Suzuki, Haruka; Shimokawa, Chikako; Olia, Alex; Obi, Seiji; Taniguchi, Tomoyo; Ishida, Hidekazu; Van Kaer, Luc; Murata, Shigeo; Tanaka, Keiji; Hisaeda, Hajime (Frontiers in Immunology, 2019-09-25)Our previous studies of protective immunity and pathology against blood stage malaria parasites have shown that not only CD4(+) T cells, but also CD8(+) T cells and macrophages, are important for host defense against blood ...
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Rudloff, Michael William; 0000-0002-2950-1218 (2023-06-15)Department: Molecular Pathology & ImmunologyTumor-specific CD8 T cells (TST) found in patients with cancer are unable to halt cancer progression. TST are dysfunctional and cannot produce effector cytokines or kill target cells1. TST dysfunction, also known as ...
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Pham, Ly Huong; 0000-0001-5980-2102 (2021-11-15)Department: Microbe-Host InteractionsDespite significant advances in medical care, infectious diseases continue to be a leading cause of death worldwide. It is estimated that infectious diseases account for a quarter of reported deaths annually. The majority ...
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McNew, Kelsey; 0000-0001-8399-831X (2022-03-02)Department: Molecular Pathology & ImmunologyType 1 Diabetes (T1D) is an autoimmune disease characterized by destruction of the pancreatic beta cells by autoreactive lymphocytes. While autoreactive CD8+ T cells, CD4+ T cells, and B cells collaborate to destroy beta ...