Browsing by Author "Karijolich, John"
Now showing items 1-5 of 5
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Thoner, Timothy Wade; 0000-0002-8084-9535 (2022-11-18)Department: Microbe-Host InteractionsViruses with multi-segmented genomes are unique in their capacity to readily exchange large amounts of genetic information via a process known as reassortment. Reassortment requires a considerable amount of genetic ...
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Gribble, Jennifer; 0000-0003-0815-5798 (2022-01-04)Department: Microbe-Host InteractionsCoronaviruses (CoVs) are a genetically diverse group of positive-sense single-stranded RNA viruses containing the largest known genome of any RNA virus, >30 kb, and responsible for the current COVID-19 pandemic (SARS-CoV-2). ...
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Hurst, Melanie Noelle; 0000-0003-0429-0714 (2022-05-16)Department: Microbe-Host InteractionsAntibiotic resistance is a growing global health threat. According to the CDC, nearly 2.8 million drug-resistant infections occur every year, killing 35,000 people annually. While research has focused on the acquisition ...
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Ye, Xiang; Zhao, Yang; Karijolich, John (PLOS Pathogens, 2019-06)Precise promoter annotation is required for understanding the mechanistic basis of transcription initiation. In the context of complex genomes, such as herpesviruses where there is extensive genic overlap, identification ...
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Dunker, William; 0000-0002-3271-4345 (2021-07-23)Department: Microbe-Host InteractionsRNA binding proteins (RBPs) interact with double or single-stranded RNA and regulate numerous stages of RNA metabolism. My thesis investigates Fused-in-sarcoma (FUS) and TAR DNA-binding protein (TDP-43), two ubiquitous ...