Browsing by Author "Jacobson, David A"
Now showing items 1-3 of 3
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Schmitz, Emily Ann; 0000-0002-5122-8991 (2022-10-17)Department: Chemical & Physical BiologyThe inositol 1,4,5triphosphate (IP3) receptor (IP3R) mediates Ca2+ release from the endoplasmic reticulum (ER) to control cytoplasmic and organellar Ca2+ concentrations. IP3Rs are co-activated by IP3 and Ca2+, inhibited ...
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Bosma, Karin Janae; 0000-0002-1221-1169 (2020-03-28)Department: Molecular Physiology & BiophysicsG6PC2 encodes a glucose-6-phosphatase catalytic subunit that is highly expressed in pancreatic islet beta cells. Genome wide association studies (GWAS) have shown that single nucleotide polymorphisms (SNPs) in the G6PC2 ...
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Perfitt, Tyler; 0000-0002-2381-3341 (2020-03-30)Department: Molecular Physiology & BiophysicsPrecise regulation of neuronal gene transcription is essential for normal brain function. For instance, neuronal depolarization leads to phosphorylation of the nuclear transcription factor CREB (pCREB), a critical transcription ...