Browsing by Author "E. Michelle Southard-Smith"
Now showing items 1-5 of 5
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Roberts, Randolph K. (2009-07-19)Department: Biological SciencesDuring spinal cord development, precursor cells transition from proliferative divisions to differentiative divisions. Traditionally proliferative divisions, which increase cell numbers, are thought to be symmetric, whereas ...
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Enteric nervous system deficits in the ganglionated bowel of Hirschsprung mouse models and patients. Musser, Melissa Anne (2014-11-26)Department: Human GeneticsHirschsprung disease, or congenital absence of ganglia in the distal intestine, occurs in approximately every 1 in 5000 live births. Although HSCR patients have the aganglionic portion of their colon removed, many suffer ...
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Chandler, Kelly Jane (2008-08-04)Department: Molecular Physiology and BiophysicsBone morphogenetic protein 4 (Bmp4) is a multi-functional, developmentally regulated gene and is essential for early mouse development. Little is known about the transcriptional regulation of Bmp4. To investigate the ...
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Linggi, Michelle S. (2005-01-27)Department: BiochemistryActivation of the p75 neurotrophin receptor leads to a variety of effects within the nervous system, including neuronal apoptosis. Both c-Jun N-terminal kinase (JNK) and the tumor suppressor p53 have been reported to be ...
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Ritter, Karen Elaine (2018-01-11)Department: NeuroscienceThe autonomic and sensory nervous systems are derived from the neural crest and are required for the normal functioning of visceral organ systems, including the bladder and urethra (lower urinary tract, LUT). Surprisingly ...