Browsing by Author "David L. Hachey"
Now showing items 1-8 of 8
-
Aerni, Hans Rudolf (2011-07-11)Department: ChemistryNew highly sensitive strategies for the analysis of proteins from selected cell populations in morphologically complex tissues have been developed. These workflows combine the single cell specificity of laser capture ...
-
Jin, Jing (2013-09-19)Department: PharmacologyBiosynthesis of lipid mediators including the leukotrienes, lipoxins, eoxins, resolvins, and protectins entails the lipoxygenase (LOX) catalyzed synthesis of an allylic epoxide intermediate, designated as leukotriene A4 ...
-
Straub, Peter Steven (2010-12-06)Department: Biomedical InformaticsShotgun liquid chromatography/tandem mass spectrometry (LC-MS/MS) technology provides data sets rich in the type of information required proteomic quantitation; however, these data are not fully exploited by existing tools. ...
-
Sun, Qian (2010-04-17)Department: Cancer BiologyThis research project is to identify FoxA1 interacting partners. In this study, a potential FoxA1 binding partner, Upstream Stimulatory Factor 2 (USF2), has been examined; its DNA binding activity was determined and the ...
-
Todd, Erik Michael (2012-12-14)Department: ChemistryRoutine analysis of cells smaller than 10 microns is a challenging task. Instruments capable of single cell analysis require advanced modifications to both laser optics and optimized instrument sensitivity to allow for the ...
-
Chacon, Almary (2007-12-13)Department: ChemistryProtein identification generally involves enzymatic digestion of proteins followed by mass spectrometry (MS) sequencing analysis of the resulting peptides, a process referred to as bottom-up proteomics. Another approach ...
-
Sun, Xiaofei (2010-07-16)Department: PharmacologyMarijuana is the most commonly used illicit drug, and its major active component, Δ9-tetrahydrocannabinol (Δ9-THC) exert its functions by targeting cannabinoid receptors, CNR1 and CNR2. There receptors are also targeted ...
-
Zheng, Yuxiang (2010-12-10)Department: PharmacologyThe goal of my thesis research is to elucidate the catalytic mechanism and physiological function of the atypical mammalian lipoxygenase, epidermal lipoxygenase-3. Although named as a lipoxygenase based on sequence homology ...