Browsing by Author "David Harrison"
Now showing items 1-7 of 7
-
Wylezinski, Lukasz Szczepan (2016-11-30)Department: Molecular Physiology and BiophysicsThe pleiotropic cytokine interleukin 2 (IL2) disrupts the blood-brain barrier and alters brain microcirculation, underlying vascular leak syndrome that complicates cancer immunotherapy with IL2. The microvascular effects ...
-
Development of hemodynamic targeted theranostic nanoparticles for the prevention of atherosclerosis Hofmeister, Lucas Hudson (2015-03-20)Department: Biomedical EngineeringIn regions of the circulation where vessels are straight and unbranched, blood flow is laminar and unidirectional. In contrast, at sites of curvature, branch points and regions distal to stenoses blood flow becomes disturbed. ...
-
O'Grady, Kristin Poole (2015-11-23)Department: Biomedical EngineeringPeripheral arterial disease (PAD) affects millions of individuals and increases the risk of myocardial infarction, stroke, and mortality. Compared to the general population, diabetic patients have a four times greater risk ...
-
Mai, Tu Hoang Anh (2014-07-17)Department: PharmacologyPHARMACOLOGY Hypo-osmotic Effects in Cardiovascular Controls: Hepatic and Renal Mechanisms Underlying the Osmopressor Response. Patients with baroreflex impairment experience a robust increase in blood ...
-
Copeland, Courtney Amanda (2017-02-08)Department: Molecular Physiology and BiophysicsCaveolin-1 (CAV1) is an essential protein for the formation of caveolae, invaginations found at the plasma membrane. Caveolae are abundant in many cell types and numerous functions have been identified, including modulating ...
-
Rhoads, Jillian Patricia (2017-08-14)Department: Microbiology and ImmunologyOxidized low-density lipoprotein (oxLDL) is known to activate inflammatory responses in a variety of cells, especially macrophages and dendritic cells. Much of the oxLDL in circulation is complexed to antibodies, and these ...
-
Prewitt, Allison Renee (2015-07-07)Department: Cell and Developmental BiologyHeritable Pulmonary Arterial Hypertension (HPAH) is a rare, fatal disease of the pulmonary vasculature for which there is no cure. The majority of HPAH patients inherit mutations in the BMP type 2-receptor gene, BMPR2, but ...