Browsing by Author "Charles Hong"
Now showing items 1-6 of 6
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Bennett, Jeffrey Scott (2013-06-17)Department: Human GeneticsA BIPHASIC ROLE FOR THE VOLTAGE-GATED SODIUM CHANNEL SCN5LAB IN CARDIAC DEVELOPMENT OF ZEBRAFISH JEFFREY S. BENNETT Dissertation under direction of Professor Dan M. Roden, M.D. Voltage-gated sodium channels (VGSCs) play ...
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Gentry, Patrick Ryan (2014-07-22)Department: Chemical and Physical BiologyThe muscarinic acetylcholine receptors (mAChRs) are a family of G protein-coupled receptors comprised of five subtypes (M1-5) expressed throughout the central nervous system (CNS). These receptors, together with their ...
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Taylor, Robert Wilson (2011-06-28)Department: Biological SciencesBIOLOGICAL SCIENCES KCTD12 PROTEINS REGULATE ULK2 TO CONTROL THE DEVELOPMENT OF ASYMMETRIC HABENULAR NEUROPIL ROBERT W. TAYLOR Dissertation under the direction of Professor Joshua T. Gamse The habenular nuclei (Hb) are ...
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Parikh, Shan S. (2018-05-21)Department: PharmacologyMutations in lamin A/C (LMNA) are the second most common contributor to genetic cases of dilated cardiomyopathy (DCM). Despite the autosomal-dominant inheritance of LMNA DCM, gene-targeted mouse models of LMNA DCM show ...
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Armstrong, Laura Craig (2017-09-21)Department: Cell and Developmental BiologyTuberous Sclerosis Complex (TSC) is a pediatric disorder of dysregulated growth and differentiation caused by loss of function mutations in either the TSC1 or TSC2 genes, which regulate mTOR kinase activity. TSC causes ...
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Andrews, Omozusi E. (2014-07-28)Department: Biological SciencesSmall noncoding RNAs including miRNAs and siRNAs play significant roles in gene regulation via the mechanism of RNA interference (RNAi) and have been exploited to conduct loss-of-function studies. The discovery that these ...