Browsing by Author "Charles C. Hong"
Now showing items 1-7 of 7
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Discovery and characterization of G protein-gated, inwardly-rectifying, potassium channel modulators Kozek, Krystian Andrzej (2018-10-16)Department: PharmacologyG protein-gated, inwardly-rectifying, potassium (K+) (GIRK) channels are important regulators of cellular excitability throughout the body. GIRK channels are composed of four subunits and exist as homomeric and heteromeric ...
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Barnett, Joshua McAlister (2011-08-08)Department: PharmacologyThe field of research into endothelial progenitor cells is complex and difficult to interpret. There are a number different investigators working on specific subpopulations that are isolated in unique ways using unique ...
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Bersell, Kevin Richard (2016-11-03)Department: PharmacologyThe application of genome science to inherited heart disease requires accurate genetic evaluation and understanding of physiologic resulting from genetic variation. Using a Long QT syndrome phenotype that is very suggestive ...
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Feaster, Tromondae Kenta (2015-11-18)Department: PharmacologyHuman induced pluripotent stem cell derived cardiomyocytes (hiPSC-CMs) have the potential to be an important tool for cardiovascular disease modeling, pre-clinical cardiotoxicity evaluation, and drug discovery. However, ...
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Dean, Benjamin Jurrien (2014-08-21)Department: NeuroscienceLeft-Right asymmetry of the CNS is a highly conserved feature across vertebrate classes. Asymmetry is manifest at the levels of function and connectivity. But the neural correlates of these asymmetries and their developmental ...
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Raphemot, Rene (2014-05-28)Department: PharmacologyInward rectifier potassium (Kir) channels are a family of two transmembrane-spanning potassium selective ion channels. Kir channels are found in all kingdoms of life where they play essential roles in regulating numerous ...
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Daniels, Richard Nathan (2010-09-28)Department: ChemistryThis dissertation describes advances in total synthesis, synthetic methodology, and chemical biology. The total synthesis and stereochemical revision of Ciliatamides A-C will be discussed in detail. Also, the total ...