Browsing by Author "Bruce D. Carter"
Now showing items 1-11 of 11
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Kraemer, Bradley Rhoads (2014-08-28)Department: NeuroscienceThe p75 Neurotrophin Receptor (p75NTR) is a critical regulator of axon pruning and apoptosis during neurodevelopment. Because the receptor has also been associated with many injurious or pathological conditions involving ...
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Cooper, Melissa Leigh (2019-06-13)Department: NeuroscienceGlaucomatous Optic Neuropathy (glaucoma) challenges retinal ganglion cell axons through sensitivity to intraocular pressure (IOP). Axons rely upon astrocyte energy stores (glycogen) to combat neurodegenerative stress. We ...
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O'Brien, Barbara Maledy Jones (2017-11-16)Department: NeuroscienceNeurons are specialized cells that communicate through electrochemical signals: a neuron receives input through dendrites and sends information through a single axon. The receptive field for each neuron is defined by sister ...
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Kashima, Daniel Tetsunori (2019-03-25)Department: NeuroscienceSubstance use disorders and depression are significant societal burdens. Both pathologies are associated with alterations of the nucleus accumbens (NAc), a reward center of the brain. The NAc is composed of two types of ...
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Huang, Xuan (2014-11-26)Department: NeuroscienceEpilepsy is a neurological disorder affecting almost one percent of the population, and genetic epilepsy are those caused by a presumed or unknown genetic factor(s). Mutations in GABAA receptors, pentameric chloride ion ...
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Benesh, Andrew Eugene (2011-12-12)Department: Cell and Developmental BiologyClass I myosins are monomeric actin-binding, ATP hydrolyzing molecular motors that are expressed in a variety of cell types, and function at the membrane-actin interface. Myosin-1d, one of eight vertebrate class I myosins, ...
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Hutton, Josiah Ewing III (2016-11-15)Department: BiochemistryBIOCHEMISTRY Oncogenic KRAS and BRAF Drive Metabolic Reprogramming in Colorectal Cancer Josiah Ewing Hutton, III. Dissertation under the direction of Professor Daniel C. Liebler Analysis of cancer cells that have ...
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Couch, Frank Benjamin IV (2014-04-17)Department: BiochemistryErrors during DNA replication lead to mutations which contribute to cancer development. To deal with these challenges, cells contain an innate machinery known as the replication stress response. ATR is the master regulator ...
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He, Siwei (2018-12-05)Department: NeuroscienceSynaptic plasticity is a hall mark of the nervous system and the foundation for learning, memory formation and the response to injury. Despite many studies in this field, the detailed mechanisms that regulate synaptic ...
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Huang, Fu (2011-03-21)Department: BiochemistryHistone lysine (K) methylation is a dynamic process that plays an important role in regulating chromatin structure and gene expression. This study has identified Jhd2, a JmjC domain-containing protein, as an H3K4-specific ...
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Hermanson, Daniel John (2014-04-08)Department: ChemistrySubstrate-selective Inhibition of Cyclooxygenase-2: Molecular Determinants, Probe Development, and In Vivo Effects. Daniel John Hermanson Dissertation under the direction of Professor Lawrence J. Marnett Cyclooxygenase-2 ...