Browsing by Author "Brian O. Bachmann, Ph.D."
Now showing items 1-6 of 6
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Allison, Brittany Ann (2016-04-07)Department: ChemistryComputational design of protein-ligand interfaces expands understanding of the basic forces involved in molecular recognition, and also contributes to the development of protein therapeutics. My dissertation research ...
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Leaptrot, Katrina Lahoma (2018-03-27)Department: ChemistryThe aim of this research was to develop strategies to advance ion mobility-mass spectrometry (IM-MS) studies via both the development of a novel, spatially multiplexed instrument and the conformational analyses of biomolecules, ...
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Craft, Kelly Marie (2019-03-22)Department: ChemistryThe increasing prevalence of antibiotic resistance coupled with a dramatically slowed rate of novel antibiotic discovery has created an environment wherein antimicrobial resistance is one of the most serious threats to ...
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McCranie, Emilianne Karyl (2015-12-16)Department: ChemistryOrthosomycins are highly decorated oligosaccharides with potent activity against a variety of Gram-positive bacteria including methicillin-resistant staphylococci and vancomycin-resistant enterococci. The research in this ...
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Mueller, Ralf (2011-08-03)Department: ChemistryThe focus of this work was to establish quantitative structure activity (QSAR, potency of allosteric modulators) and property (QSPR, carbon chemical shifts) relations for molecules with known structure and activity/property ...
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Keithly, Mary Elizabeth (2016-07-08)Department: ChemistryStructure, substrate selectivity, and catalytic mechanism of the fosfomycin resistance enzyme, FosB, from Gram-positive pathogens By: Mary E. Keithly Fosfomycin, a broad spectrum antibiotic, is used clinically to treat ...