Browsing by Author "Bastarache, Lisa"

Now showing items 1-3 of 3

    • A Drug-Based Phenotype Risk Score for Opioid-Related Adverse Events 
      Tang, Leigh Anne; 0000-0002-6431-6069 (2022-05-16)
      Department: Biomedical Informatics
      Opioids are commonly prescribed for chronic pain. However, even when titrated appropriately, opioids may result in opioid-related adverse events (OAEs). Previous studies have defined OAEs categorically (e.g., did/did not ...
    • IgG4-related disease: Association with a rare gene variant expressed in cytotoxic T cells 
      Newman, John H.; Shaver, Aaron; Sheehan, Jonathan H.; Mallal, Simon; Bastarache, Lisa; Riebau, Derek; Pilkinton, Mark; Smith, Scott A.; McDonnell, Wyatt J.; Capra, John A.; Meiler, Jens; Cogan, Joy; Hamid, Rizwan; Phillips, John A., III (Molecular Genetrics & Genome Medicine, 2019-06)
      BackgroundFamily screening of a 48-year-old male with recently diagnosed IgG4-related disease (IgG4-RD) revealed unanticipated elevations in plasma IgG4 in his two healthy teenaged sons. MethodsWe performed gene sequencing, ...
    • Mapping ICD-10 and ICD-10-CM Codes to Phecodes: Workflow Development and Initial Evaluation 
      Wu, Patrick; Gifford, Aliya; Meng, Xiangrui; Li, Xue; Campbell, Harry; Varley, Tim; Zhao, Jaun; Carroll, Robert; Bastarache, Lisa; Denny, Joshua C.; Theodoratou, Evropi; Wei, Wei-Qi (JMIR Medical Informatics, 2019)
      Background: The phecode system was built upon the International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) for phenome-wide association studies (PheWAS) using the electronic health record ...