Browsing by Author "Anne K. Kenworthy"
Now showing items 1-9 of 9
-
Nyhoff, Lindsay Elizabeth (2017-03-31)Department: Microbiology and ImmunologyBruton’s tyrosine kinase (BTK) is a tec-family kinase present in B lymphocytes and innate immune cells. BTK is an important regulator of B cell autoreactivity. Innate-like autoreactive-prone B1, anergic An1, and transgenic ...
-
Archuleta, Tara Lakshimi (2014-05-29)Department: Chemical and Physical BiologyChlamydiae species are obligate intracellular pathogens that utilize a type three-secretion system (T3SS) to deliver effector proteins and manipulate host cell processes. T3SSs are composed of cytosolic components, a needle ...
-
Chandrasekaran, Ramyavardhanee (2017-11-27)Department: Microbiology and ImmunologyClostridium difficile infection affects a significant number of hospitalized patients in the United States. Two homologous exotoxins, TcdA and TcdB, are the major virulence factors in C. difficile pathogenesis. The toxins ...
-
McConnell, Russell E. (2010-03-22)Department: Cell and Developmental BiologyEpithelial cells lining the lumen of the small intestine, called enterocytes, possess an exquisitely ordered array of microvilli collectively referred to as the brush border (BB). Microvilli are actin-rich membrane protrusions ...
-
Hankins, Hannah Marcille (2016-04-19)Department: Biological SciencesWithin a eukaryotic cell is a steady stream of vesicles budding from and fusing to different membranes to generate distinct organelles. The formation and movement of these vesicles is a complicated and interconnected process ...
-
Raf-1 kinase regulates intestinal epithelial cell survival in response to pro-inflammatory stimuli Edelblum, Karen Leigh (2008-04-08)Department: Cell and Developmental BiologyThe maintenance of the intestinal epithelium is dependent upon controlled regulation of cell proliferation and apoptosis, or programmed cell death. Dysregulation of either of these processes can compromise the integrity ...
-
Kim, Robert Jaewook (2012-04-21)Department: Chemical and Physical BiologyAdenovirus has been studied for many years for its potential as a gene delivery vector in gene therapy applications. One of the more challenging problems under research is the design of Adenoviral vectors that can be ...
-
Bristow, Jeanne Malloy (2010-01-08)Department: Biological SciencesBIOLOGICAL SCIENCES THE RHO FAMILY GEF ASEF2 REGULATES ADHESION DYNAMICS AND THEREFORE CELL MIGRATION BY MODULATING RAC AND RHO ACTIVITY JEANNE MALLOY BRISTOW Dissertation under the direction of Assistant Professor Donna ...
-
Hong, Nan Hyung (2015-03-19)Department: Cancer BiologyThe branched actin regulator cortactin is a central element connecting signaling pathways with the actin cytoskeleton and plays a role in diverse cellular processes. Cortactin-mediated actin assembly is known to contribute ...