Browsing by Author "Alfred George"
Now showing items 1-5 of 5
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Gurba, Katharine Nicole (2013-07-18)Department: NeuroscienceGABAA receptors are pentameric, ligand-gated chloride channels that mediate the majority of fast inhibition in the brain. Because they are assembled from an array of 19 subunit subtypes, GABAA receptors are remarkable ...
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Fentress, Hugh Montrell (2005-07-12)Department: NeuroscienceThis dissertation describes pharmacological studies of the functional consequences of the Cys23Ser single nucleotide polymorphism (SNP) in two different edited versions of the human 5-HT2C receptor as well as evaluation ...
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Hawkins, Nicole Alise (2013-11-25)Department: NeuroscienceEpilepsy is a neurological disorder affecting approximately 3 million Americans. Two-thirds of patients diagnosed with epilepsy have no known cause for their disease, however recent evidence suggests most result from complex ...
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Anderson, Lyndsey Leigh (2014-03-18)Department: PharmacologyPHARMACOLOGY Pharmacological and Genetic Rescue of Idiopathic Epilepsies Lyndsey Leigh Anderson Dissertation under the direction of Professor Alfred George, Jr. Epilepsy is a common neurological disorder affecting ...
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Thiel, William Howard (2008-12-02)Department: PharmacologyCa2+ activated signaling pathways coordinate contraction in the heart, but these pathways cause disease upon excessive activation. Intracellular Ca2+ activates the multifunctional Ca2+ and calmodulin dependent protein ...