Browsing by Title
Now showing items 4730-4749 of 17713
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(Vanderbilt University, 2016-05-11)
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(Vanderbilt University., 2008-07-09)
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(2016-11-28)Department: EnglishIn this intervention, I evaluate the literary work of Ralph Ellison with respect to other black writers of his time to explore the precise-rather than perceived-differences and similarities between his aesthetic and political ...
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(Vanderbilt University. Peabody College, 2022)This paper is a review of two years of graduate studies at Vanderbilt University, which includes three parts: Teaching Philosophy, Artifact Analysis, and Application to Practice. In the teaching philosophy, I describe my ...
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(2023-03-23)Department: NeuroscienceCentral nervous system (CNS) immune privilege is imparted by a complex set of mechanisms designed to protect the fragile brain tissue. Brain endothelial cells (BECs), the main functional unit of the blood-brain barrier ...
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(2022-03-04)Department: NeuroscienceThe suprachiasmatic nucleus (SCN) of the hypothalamus serves as a central circadian oscillator that receives direct retinal light input and synchronizes (or entrains) endogenous daily rhythms in behavior and physiology to ...
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(2013-04-09)Department: BiochemistryGiven the fundamental roles of histone deacetylases (HDACs) in the regulation of DNA repair, replication, transcription and chromatin structure, it is fitting that therapies targeting HDAC activities are now being explored ...
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(2020-01-24)Department: ChemistryTo investigate this dynamic response at the level of individual molecular species, human embryonic kidney (HEK)-293 cells were stably transfected with hemagglutinin (HA)-tagged human muscarinic-1 acetylcholine receptors ...
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(2023-03-24)Department: Chemical EngineeringThe majority of breast cancer patients receive radiation therapy. Although this treatment improves overall outcomes, patients with triple negative breast cancer (TNBC) have a significantly higher risk of distant and ...
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(2015-07-09)Department: Biological SciencesInitiation of DNA Replication is a highly regulated process and is characterized by the conversion of inactive Mcm2-7 double hexamer around dsDNA to an active helicase consisting of Mcm2-7 single hexamer which encircles ...
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(2018-07-22)Department: Molecular Physiology and BiophysicsThe phagocytic nature and oxidative resiliency of macrophages not only allows them to function as innate immune cells but also to respond to specific tissue needs, such as iron homeostasis. MFehi ATMs are a subtype of ...
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(2019-12-04)Department: NeuroscienceManganese is an essential micronutrient, required for the activity of many enzymes. Our lab has established that cellular and mouse models of Huntington’s Disease (HD) exhibit reduced striatal Mn bioavailability. This ...
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(2022-05-16)Department: Microbe-Host InteractionsAntibiotic resistance is a growing global health threat. According to the CDC, nearly 2.8 million drug-resistant infections occur every year, killing 35,000 people annually. While research has focused on the acquisition ...
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(2016-01-13)Department: Cell and Developmental BiologyProper regulation of gene transcription is an essential process for any cell. Failure to precisely control the procedure of transcription can lead to developmental defects, disease, and even death. Within the last 20 years, ...
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(2014-05-27)Department: Cell and Developmental BiologyA critical step during gene expression is the directional export of nuclear messenger (m)RNA through nuclear pore complexes (NPCs) to the cytoplasm. During export, Gle1 in conjunction with inositol hexakisphosphate (IP6) ...
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(2019-11-12)
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(Vanderbilt University. Dept. of History, 2005-04-15)
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(2020-11-06)Department: EnglishAnn Radcliffe’s second novel—A Sicilian Romance—is often derided as an ‘immature’ and ‘directionless’ narrative; this essay seeks to complicate these evaluations by viewing the text through the lens of embodied cognition ...
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(2019-09-13)Department: Special EducationThe capacity to read nonfiction text with understanding is of obvious and vital importance, yet many students struggle to do so. This randomized control trial extends previous research by contrasting the efficacy of a ...