Browsing by Title
Now showing items 3756-3775 of 17713
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(2014-03-17)Department: Biomedical EngineeringNucleic acid extraction is a significant roadblock to the widespread use of molecular detection strategies such as PCR in resource-limited settings. This thesis explores the potential to simplify nucleic acid extractions ...
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(2012-04-05)Department: Biomedical EngineeringMitral valve prolapse is one subtype of mitral valve disease and is characterized by enlarged leaflets that are often thickened and have disrupted collagen architecture. The increased surface area of leaflets with mitral ...
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(2013-12-04)Department: Biomedical EngineeringAdvantages of high-purity germanium (HPGe) detectors over traditional scintillator detectors include excellent energy resolution, approximately 1% at 140 keV, which allows for better scatter rejection and simple multi-isotope ...
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(2018-03-27)Department: ChemistryThe aim of this research was to develop strategies to advance ion mobility-mass spectrometry (IM-MS) studies via both the development of a novel, spatially multiplexed instrument and the conformational analyses of biomolecules, ...
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(2012-12-14)Department: ChemistryI describe a methodology for preparing and using a standard target for calibrating, laser alignment and focusing of MALDI imaging mass spectrometry instruments. The target is constructed by simple detachment patterning ...
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(2014-07-17)Department: ChemistryCuInS2 is a ternary semiconductor material with potential alternative energy applications in photovoltaic devices and in systems designed for photocatalytic water reduction. To date, the majority of research into CuInS2 ...
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(2017-08-07)Department: Biomedical EngineeringHemodialysis is the primary lifeline for nearly half a million Americans with end-stage renal disease (ESRD). Unfortunately, 40 – 60% of these access sites occlude and fail within the first year. This causes significant ...
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(2020-03-25)Department: Environmental EngineeringThe development of a flexible methodology to comprehensively identify the hazards, and determine the most significant risks associated with the operation of advanced nuclear reactor designs, is required in order to ...
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(2022-05-16)Department: Biomedical EngineeringTriple negative breast cancer (TNBC) is characterized by a lack of estrogen receptor, progesterone receptor, and HER2. Patients with TNBC therefore cannot benefit from treatment with one of the molecularly targeted therapies ...
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(2010-03-30)Department: Civil EngineeringOver the past decade, catastrophic events such as the World Trade Center attacks, Hurricane Katrina, and the Minneapolis bridge collapse have affected societal perception of the risks affecting our lives. It has also led ...
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(Law and Contemporary Problems, 1997)The purpose of this article is to describe the development of an early identification and response model of malpractice prevention that is designed to achieve these objectives. The article begins with a rationale for the ...
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(2017-08-11)Department: Biomedical EngineeringBreast cancer is the most common cancer in women and the second highest cause of cancer related deaths among women in the United States. Most breast cancers are treated by some form of surgical intervention. Breast ...
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(2020-06-02)Department: ChemistryHere in, we describe the optimization of high-affinity, choline up-take transporter (CHT) antagonist, ML352, to improved in vivo tool compound, VU6001221. VU6001221, a potent and selective CHT inhibitor with significantly ...
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(2021-05-11)Department: Biomedical EngineeringLoss of parathyroid function (hypoparathyroidism) is an unintended consequence of endocrine neck surgeries. This leads to an inability of the patient to maintain healthy levels of blood calcium, as the parathyroid glands ...
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(2016-04-15)Department: Biomedical EngineeringThe inability to identify the parathyroid glands is a significant challenge during endocrine procedures. Successful parathyroid and thyroid surgeries require careful resection of diseased tissue and preservation of normal ...
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(2018-10-30)Department: PhysicsOver the last few decades the capabilities of atomic-resolution imaging techniques such as Scanning-Transmission-Electron-Microscopy (STEM) have greatly increased. The data acquisition rate of modern of atomic-resolution ...
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(Childhood Obesity, 2020)To develop and test brief nutrition and physical activity screening questions for children ages 2–11 years that could be used as a pragmatic screening tool to tailor counseling, track behavior change, and improve population ...
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(2021-08-13)Department: ChemistryBiohybrid solar cells utilizing the plant protein complex Photosystem I (PSI) as the key photoactive ingredient are studied for their ability to reduce the cost and environmental impacts of solar energy harvesting technologies. ...
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(2004-12-01)Department: PsychologyIn a sample of 515 children (grades 2, 4, and 6), we examined parenting and negative life events as predictors of depressive cognitions, specifically depressogenic attributional style, depressive cognitive schemas, and low ...
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(2012-03-31)Department: PsychologyThe link between the experience of peer victimization (PV) and future psychological maladjustment, particularly depressive symptoms, has been consistently documented; however, little is known about intermediary cognitive ...