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Trends in comparative efficacy and safety of malaria control interventions for maternal and child health outcomes in Africa: a study protocol for a Bayesian network meta-regression exploring the effect of HIV and malaria endemicity spectrum
(BMJ Open, 2019-06)
Introduction Unprecedented global efforts to prevent malaria morbidity and mortality in sub-Saharan Africa have saved hundreds of thousands of lives across the continent in the last two decades. This study aims to determine ...
The Salivary Microbiome Is Altered in Children With Eosinophilic Esophagitis and Correlates With Disease Activity
(Clinical and Translational Gastroenterology, 2019-05-20)
OBJECTIVES: Eosinophilic esophagitis (EoE) is an allergen-mediated inflammatory disease affecting the esophagus. Although microbial communities may affect the host immune responses, little is known about the role of the ...
Novel HLA Class I Alleles Outside the Extended DR3 Haplotype Are Protective against Autoimmune Hepatitis
(Clinical and Translational Gastroenterology, 2019-06-18)
Abstract
INTRODUCTION: HLA class II allele, DRB1*03:01, is the most common genetic risk factor for autoimmune hepatitis (AIH), but other unrecognized HLA related risks exist.
METHODS: We compared the HLA class I (A, ...
Genomic analysis of serologically untypable human enteroviruses in Taiwan
(JOURNAL OF BIOMEDICAL SCIENCE, 2019-07-03)
BackgroundHuman enteroviruses contain over 100 serotypes. We have routinely conducted enterovirus surveillance in northern Taiwan; but about 10% of isolates could not be serotyped using traditional assays. Next-generation ...
Gut microbiota modulates lung fibrosis severity following acute lung injury in mice
(Communications Biology, 2023-01-13)
Independent studies demonstrate the significance of gut microbiota on the pathogenesis of chronic lung diseases; yet little is known regarding the role of the gut microbiota in lung fibrosis progression. Here we show, using ...