Browsing Electronic Theses and Dissertations by Subject "Xenopus"

Now showing items 1-6 of 6

    • Analysis of Bves function in vesicular transport and cell morphology 
      Carter, Hillary Hager (2009-12-14)
      Department: Cell and Development Biology
      Bves is a transmembrane protein that influences cell migration, motility, and epithelial integrity through previously undefined mechanisms. In this dissertation, I present evidence that identifies the molecular basis for ...
    • High resolution studies of Xnr1 signaling and left-right asymmetry in Xenopus 
      Marjoram, Lindsay Taylor (2010-12-04)
      Department: Cell and Developmental Biology
      The spatiotemporally dynamic distribution of instructive ligands within embryonic tissue, and their feedback antagonists, including inherent stabilities and rates of clearance, are affected by interactions with cell surfaces ...
    • Receptor-Mediated Activation of Canonical Wnt Signaling 
      Cselenyi, Christopher Stephen (2008-07-26)
      Department: Cell and Developmental Biology
      Wnt/beta-catenin signaling controls various cell fates in metazoan development and is misregulated in several cancers and developmental disorders. Binding of a Wnt ligand to its transmembrane coreceptors, Frizzled (Fz) ...
    • Regulation of the Wnt Pathway by TGFbeta and DYRK2: Mechanisms of Disease and Signal Transduction 
      Baskir, Rubin Sam (2016-08-05)
      Department: Interdisciplinary Studies: Focus on Clinical and Cellular Biology
      My thesis is composed of two independent projects related by the Wnt signaling transduction pathway. The first project provides evidence that vascular-associated adult lung mesenchymal stem cells (MSCs) respond to ...
    • Replication Fork Uncoupling Causes Nascent Strand Degradation and Fork Reversal 
      Kavlashvili, Tamar; 0000-0003-3827-8975 (2022-11-22)
      Department: Biochemistry
      Genotoxic agents can cause nascent strand degradation (NSD) and fork reversal during DNA replication. NSD and fork reversal are crucial biochemical mechanisms that maintain genome stability and they are frequently exploited ...
    • The effect of post-translational modifications on Xlefty function 
      Westmoreland, Joby Jackson (2007-11-28)
      Department: Cell and Developmental Biology
      The Nodal and Nodal-related morphogens are utilized for the specification of distinct cellular identity throughout development by activating discrete target genes in a concentration-dependant manner. Lefty is the principal ...